About: Association analysis of seven candidate genes with performance traits in Czech Large White pigs

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In this study association analyses were performed between genes tagged SNP (IGF2, NAMPT, DGAT1, MYF4, MC3R, MC4R and MYOD1), performance traits (backfat thickness, lean meat content, average daily gain from birth to the end of the test, average daily gain in test) and estimated breeding values (EBVs) in a population of Czech Large White sows (n = 101). Genotyping of all SNPs was performed by SNapShot with the exception of SNP within NAMPT gene for which HpaII PCR-RFLP assay was used. The following significant associations between genes tagged SNPs and traits or EBVs were found out: DGAT1 - lean meat content (AG > AA, P <= 0.05), MC4R - EBV for lean meat content (GG > AA, P <= 0.05; GG > AG, P <= 0.05), IGF2 - EBV for reproduction (piglets born alive in the second and subsequent parity) (AG > AA, P <= 0.05) and total EBV (AG > AA, P <= 0.01) and MC3R - EBV for average daily gain (CT > TT, P <= 0.05). In this study association analyses were performed between genes tagged SNP (IGF2, NAMPT, DGAT1, MYF4, MC3R, MC4R and MYOD1), performance traits (backfat thickness, lean meat content, average daily gain from birth to the end of the test, average daily gain in test) and estimated breeding values (EBVs) in a population of Czech Large White sows (n = 101). Genotyping of all SNPs was performed by SNapShot with the exception of SNP within NAMPT gene for which HpaII PCR-RFLP assay was used. The following significant associations between genes tagged SNPs and traits or EBVs were found out: DGAT1 - lean meat content (AG > AA, P <= 0.05), MC4R - EBV for lean meat content (GG > AA, P <= 0.05; GG > AG, P <= 0.05), IGF2 - EBV for reproduction (piglets born alive in the second and subsequent parity) (AG > AA, P <= 0.05) and total EBV (AG > AA, P <= 0.01) and MC3R - EBV for average daily gain (CT > TT, P <= 0.05). (en)
Title	Association analysis of seven candidate genes with performance traits in Czech Large White pigs Association analysis of seven candidate genes with performance traits in Czech Large White pigs (en)
skos:prefLabel	Association analysis of seven candidate genes with performance traits in Czech Large White pigs Association analysis of seven candidate genes with performance traits in Czech Large White pigs (en)
skos:notation	RIV/67985904:_____/11:00377998!RIV13-AV0-67985904
http://linked.open...avai/riv/aktivita	S Z
http://linked.open...avai/riv/aktivity	S, Z(AV0Z50450515)
http://linked.open...iv/cisloPeriodika	8
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Weisz, Filip
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav živočišné fyziologie a genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	187314
http://linked.open...ai/riv/idVysledku	RIV/67985904:_____/11:00377998
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	pig; genotyping; SNP (en)
http://linked.open.../riv/klicoveSlovo	SNP genotyping pig
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[49B9F9A65561]
http://linked.open...i/riv/nazevZdroje	Czech Journal of Animal Science
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	56
http://linked.open...iv/tvurceVysledku	Chalupová, P. Knoll, A. Urban, T. Weisz, Filip
http://linked.open...ain/vavai/riv/wos	000295250900001
http://linked.open...n/vavai/riv/zamer	Genetic, functional and developmental potential of animal cells, tissues and organisms: their use in medicine, ecology and agriculture
issn	1212-1819
number of pages	8 (xsd:int)

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