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Description
  • Ovarian hyperstimulation syndrome (OHSS) is a serious complication of in vitro fertilisation therapy using hormonal stimulation of ovaries. Current diagnosis is not sufficient and could be significantly improved if a protein biomarker(s) could be identified in patient follicular fluid (HFF). In search for new potential diagnostic and prognostic biomarker(s) of OHSS we have used a combination of immunoaffinity depletion, 2-D LC and 2-DE to obtain 2D protein profiles of HFF from OHSS positive and OHSS negative women. The protein maps were evaluated using software tools and protein spots or bands significantly increased or decreased in HFF of OHSS positive and OHSS negative women were identified using MS. In total, we identified 20 proteins and 3 of them were shared between two different 2D technologies. Most of the identified proteins belong to different functional groups including the complement cascade, transport, blood coagulation, acute phase response and inflammation.
  • Ovarian hyperstimulation syndrome (OHSS) is a serious complication of in vitro fertilisation therapy using hormonal stimulation of ovaries. Current diagnosis is not sufficient and could be significantly improved if a protein biomarker(s) could be identified in patient follicular fluid (HFF). In search for new potential diagnostic and prognostic biomarker(s) of OHSS we have used a combination of immunoaffinity depletion, 2-D LC and 2-DE to obtain 2D protein profiles of HFF from OHSS positive and OHSS negative women. The protein maps were evaluated using software tools and protein spots or bands significantly increased or decreased in HFF of OHSS positive and OHSS negative women were identified using MS. In total, we identified 20 proteins and 3 of them were shared between two different 2D technologies. Most of the identified proteins belong to different functional groups including the complement cascade, transport, blood coagulation, acute phase response and inflammation. (en)
Title
  • Ovarian hyperstimulation syndrome biomarker(s) search in human follicular fluid
  • Ovarian hyperstimulation syndrome biomarker(s) search in human follicular fluid (en)
skos:prefLabel
  • Ovarian hyperstimulation syndrome biomarker(s) search in human follicular fluid
  • Ovarian hyperstimulation syndrome biomarker(s) search in human follicular fluid (en)
skos:notation
  • RIV/67985904:_____/09:00338300!RIV10-AV0-67985904
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(1QS500450568), Z(AV0Z50200510), Z(AV0Z50450515)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 332365
http://linked.open...ai/riv/idVysledku
  • RIV/67985904:_____/09:00338300
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Ovarian hyperstimulation syndrom; Follicular fluid; Biomarkers (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [B0A3A54DDA0E]
http://linked.open...v/mistoKonaniAkce
  • Budapešť
http://linked.open...i/riv/mistoVydani
  • Budapest
http://linked.open...i/riv/nazevZdroje
  • 3rd Central and Eastern Proteomics Conference, 2009
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Halada, Petr
  • Kavan, Daniel
  • Gadher, S. J.
  • Hrabáková, Rita
  • Jarkovská, Karla
  • Kovářová, Hana
  • Rezábek, K.
  • Skalníková, Helena
  • Martinková, Jiřina
http://linked.open...vavai/riv/typAkce
http://linked.open.../riv/zahajeniAkce
http://linked.open...n/vavai/riv/zamer
number of pages
http://purl.org/ne...btex#hasPublisher
  • Hungarian proteomic society
https://schema.org/isbn
  • 978-963-9319-99-8
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