About: Effect of anti-cancer drug cis-platin on leukemia cells-protein profiling using three independent analytical techniques

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About: Effect of anti-cancer drug cis-platin on leukemia cells-protein profiling using three independent analytical techniques Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Proteomic profiling of cancer cells was carried out with a view to adressing leukemia and its treatment with perspective towards novel diagnostic and / or treatment modalities. Advances in cancer therapeutics and challenges for better patient outcome has lead to demands for individualised or personalised therapy and targeting of tumors for a better outcome. earlier protein changes that precede the on-set of apoptosis or changes in post-translational modifications were studied using proteomic analysis of cells treated with anti-cancer drug Cis-platin. To reliably quantify maximum number of proteins in the whole cell lysate, combination of three proteomic methodologies namely 2-DE electrophoresis, PF 2D liquid chromatography and SILAC were used Proteomic profiling of cancer cells was carried out with a view to adressing leukemia and its treatment with perspective towards novel diagnostic and / or treatment modalities. Advances in cancer therapeutics and challenges for better patient outcome has lead to demands for individualised or personalised therapy and targeting of tumors for a better outcome. earlier protein changes that precede the on-set of apoptosis or changes in post-translational modifications were studied using proteomic analysis of cells treated with anti-cancer drug Cis-platin. To reliably quantify maximum number of proteins in the whole cell lysate, combination of three proteomic methodologies namely 2-DE electrophoresis, PF 2D liquid chromatography and SILAC were used (en)
Title	Effect of anti-cancer drug cis-platin on leukemia cells-protein profiling using three independent analytical techniques Effect of anti-cancer drug cis-platin on leukemia cells-protein profiling using three independent analytical techniques (en)
skos:prefLabel	Effect of anti-cancer drug cis-platin on leukemia cells-protein profiling using three independent analytical techniques Effect of anti-cancer drug cis-platin on leukemia cells-protein profiling using three independent analytical techniques (en)
skos:notation	RIV/67985904:_____/09:00338290!RIV10-MSM-67985904
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(LC07017), Z(AV0Z50200510), Z(AV0Z50450515)
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Kovářová, Hana Hrabáková, Rita Skalníková, Helena Tylečková, Jiřina
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav živočišné fyziologie a genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	312000
http://linked.open...ai/riv/idVysledku	RIV/67985904:_____/09:00338290
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Cis-platin; CEM T-lymphoblastic leukemia; 2D-electrophoresis (en)
http://linked.open.../riv/klicoveSlovo	2D-electrophoresis CEM T-lymphoblastic leukemia Cis-platin
http://linked.open...ontrolniKodProRIV	[18B74E6D5E05]
http://linked.open...v/mistoKonaniAkce	Stockholm
http://linked.open...i/riv/mistoVydani	Veszprem
http://linked.open...i/riv/nazevZdroje	3rd EuPA Congress Clinical Proteomics
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	12 (xsd:int)
http://linked.open...vavai/riv/projekt	Oncoproteomics Centre
http://linked.open...UplatneniVysledku	2009
http://linked.open...iv/tvurceVysledku	Man, Petr Novák, Petr Gadher, S. J. Havlíček, Vladimír Hrabáková, Rita Kovářová, Hana Skalníková, Helena Pompach, Petr Hajduch, M. Strohalm, Martin Džubák, P. Martinková, Jiřina
http://linked.open...vavai/riv/typAkce	EUR - Evropská
http://linked.open.../riv/zahajeniAkce	2009-06-14 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Microorganisms in Research and Biotechnology Genetic, functional and developmental potential of animal cells, tissues and organisms: their use in medicine, ecology and agriculture
number of pages	4 (xsd:int)
http://purl.org/ne...btex#hasPublisher	OOK-PRESS Kft
https://schema.org/isbn	978-963-86156-4-0

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