About: In-depth study of the human follicular fluid for a diagnostic / prognostic marker of ovarian hyperstimulation syndrome

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About: In-depth study of the human follicular fluid for a diagnostic / prognostic marker of ovarian hyperstimulation syndrome Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Ovarian hyperstimulation syndrome (OHSS) is a serious complication of in vitro fertilisation therapy using hormonal stimulation of ovaries. Current diagnosis is not sufficient and could be significantly improved if a protein biomarker(s) could be identified in patient follicular fluid (HFF). In search for new potential diagnostic and prognostic biomarker(s) of OHSS we have used a combination of immunoaffinity depletion, 2-D LC and 2-DE to obtain 2D protein profiles of HFF from OHSS positive and OHSS negative women. The protein maps were evaluated using software tools and protein spots or bands significantly increased or decreased in HFF of OHSS positive and OHSS negative women were identified using MS. In total, we identified 20 proteins and 3 of them were shared between two different 2D technologies. Most of the identified proteins belong to different functional groups including the complement cascade, transport, blood coagulation, acute phase response and inflammation. Ovarian hyperstimulation syndrome (OHSS) is a serious complication of in vitro fertilisation therapy using hormonal stimulation of ovaries. Current diagnosis is not sufficient and could be significantly improved if a protein biomarker(s) could be identified in patient follicular fluid (HFF). In search for new potential diagnostic and prognostic biomarker(s) of OHSS we have used a combination of immunoaffinity depletion, 2-D LC and 2-DE to obtain 2D protein profiles of HFF from OHSS positive and OHSS negative women. The protein maps were evaluated using software tools and protein spots or bands significantly increased or decreased in HFF of OHSS positive and OHSS negative women were identified using MS. In total, we identified 20 proteins and 3 of them were shared between two different 2D technologies. Most of the identified proteins belong to different functional groups including the complement cascade, transport, blood coagulation, acute phase response and inflammation. (en)
Title	In-depth study of the human follicular fluid for a diagnostic / prognostic marker of ovarian hyperstimulation syndrome In-depth study of the human follicular fluid for a diagnostic / prognostic marker of ovarian hyperstimulation syndrome (en)
skos:prefLabel	In-depth study of the human follicular fluid for a diagnostic / prognostic marker of ovarian hyperstimulation syndrome In-depth study of the human follicular fluid for a diagnostic / prognostic marker of ovarian hyperstimulation syndrome (en)
skos:notation	RIV/67985904:_____/09:00338289!RIV10-MSM-67985904
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1QS500450568), P(LC07017), Z(AV0Z50200510), Z(AV0Z50450515)
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Kovářová, Hana Hrabáková, Rita Jarkovská, Karla Skalníková, Helena Tylečková, Jiřina
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav živočišné fyziologie a genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	319006
http://linked.open...ai/riv/idVysledku	RIV/67985904:_____/09:00338289
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	human folicular fluid; ovarian hyperstimulation syndrome; gel elctrophoresis (en)
http://linked.open.../riv/klicoveSlovo	gel elctrophoresis human folicular fluid ovarian hyperstimulation syndrome
http://linked.open...ontrolniKodProRIV	[2656D754DB82]
http://linked.open...v/mistoKonaniAkce	Stockholm
http://linked.open...i/riv/mistoVydani	Veszprem
http://linked.open...i/riv/nazevZdroje	3rd EuPA Congress Clinical Proteomics
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Female gametes - regulation of their meiotic and developmental competence and possibilities of its practical application Oncoproteomics Centre
http://linked.open...UplatneniVysledku	2009
http://linked.open...iv/tvurceVysledku	Halada, Petr Kavan, Daniel Gadher, S. J. Hrabáková, Rita Jarkovská, Karla Kovářová, Hana Skalníková, Helena Martinková, Jiřina
http://linked.open...vavai/riv/typAkce	EUR - Evropská
http://linked.open.../riv/zahajeniAkce	2009-06-14 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Microorganisms in Research and Biotechnology Genetic, functional and developmental potential of animal cells, tissues and organisms: their use in medicine, ecology and agriculture
number of pages	3 (xsd:int)
http://purl.org/ne...btex#hasPublisher	OOK-PRESS Kft
https://schema.org/isbn	978-963-86156-4-0

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