About: Accessing stem cells via proteomics

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Stem cells have two important characteristics that distinguish them from other cells: the ability to self-renew through cell division for prolonged period and to differentiate into multiple cells with specialised functions. The availability of approaches to investigate at complex level epigenome and proteome including signal transduction pathways (phosphoproteome), has significantly contributed to basic understanding of stem cell biology and produced data characterising proteins involved in mechanisms that regulate stem cell proliferation and differentiation. More recently, Proteome Biology of Stem Cells, a joint initiative shared by International Society for Stem Cell Research and Human Proteome Organisation was established. Considering the many challenges in the field of stem cell biology, this initiative intends to be beneficial for many researchers and to increase the value of proteomics in these endeavours. Stem cells have two important characteristics that distinguish them from other cells: the ability to self-renew through cell division for prolonged period and to differentiate into multiple cells with specialised functions. The availability of approaches to investigate at complex level epigenome and proteome including signal transduction pathways (phosphoproteome), has significantly contributed to basic understanding of stem cell biology and produced data characterising proteins involved in mechanisms that regulate stem cell proliferation and differentiation. More recently, Proteome Biology of Stem Cells, a joint initiative shared by International Society for Stem Cell Research and Human Proteome Organisation was established. Considering the many challenges in the field of stem cell biology, this initiative intends to be beneficial for many researchers and to increase the value of proteomics in these endeavours. (en) Koncept tkáňových kmenových buněk jako pluripotentních progenitorů pro různé tkáně vedl ke zvýšenému zájmu o výzkum kmenových buněk. Dostupnost komplexních přístupů ke studiu epigenomu, proteomů a signáních cest významně přispívá k zásadnímu pochopení mechanismů, které regulují proliferaci a diferenciaci kmenových buněk. Nedávno byla tato aktivita povrzena ustavením iniciativy Proteomová Biologie Kmenových Buněk ve spolupráci ISSCR a HUPO. (cs)
Title	Accessing stem cells via proteomics Poznávání kmenových buněk prostřednictvím proteomiky (cs) Accessing stem cells via proteomics (en)
skos:prefLabel	Accessing stem cells via proteomics Poznávání kmenových buněk prostřednictvím proteomiky (cs) Accessing stem cells via proteomics (en)
skos:notation	RIV/67985904:_____/08:00310175!RIV09-AV0-67985904
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(AV0Z50450515)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Kovářová, Hana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav živočišné fyziologie a genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	354717
http://linked.open...ai/riv/idVysledku	RIV/67985904:_____/08:00310175
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	stem cella; proteomics (en)
http://linked.open.../riv/klicoveSlovo	proteomics stem cella
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[7D95AB11715B]
http://linked.open...i/riv/nazevZdroje	European Pharmaceutical Rewiew
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...UplatneniVysledku	2008
http://linked.open...v/svazekPeriodika	-
http://linked.open...iv/tvurceVysledku	Gadher, S. J. Kovářová, Hana
http://linked.open...n/vavai/riv/zamer	Genetic, functional and developmental potential of animal cells, tissues and organisms: their use in medicine, ecology and agriculture
issn	1360-8606
number of pages	8 (xsd:int)

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