About: Effect of hyaluronidase and PEG chain conjugation on the biologic and antitumour activity of RNase A

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About: Effect of hyaluronidase and PEG chain conjugation on the biologic and antitumour activity of RNase A Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Subkutánní aplikace bovinní RNase A kojugované s Hyase (bovidní hyaluronidasa,polyethylen glykolem /PEG) snižoval aspermatogenní efekt. Melanomový nádor rostoucí na athymických myších však byl podstatně zmenšen (cs) Subcutaneous application of bovine RNase A conjugated to HYase (bovine hyaluronidase), polyethylene glycol(PEG)and HYase+PEG resulted in a marker reduction of the width of the spermatogenic layers of the mouse testes. The number of sperms in caput epididymidis was significantly desreased in mice injected with conjugated RNase A Subcutaneous application of bovine RNase A conjugated to HYase (bovine hyaluronidase), polyethylene glycol(PEG)and HYase+PEG resulted in a marker reduction of the width of the spermatogenic layers of the mouse testes. The number of sperms in caput epididymidis was significantly desreased in mice injected with conjugated RNase A (en)
Title	Effect of hyaluronidase and PEG chain conjugation on the biologic and antitumour activity of RNase A Effect of hyaluronidase and PEG chain conjugation on the biologic and antitumour activity of RNase A (en) Působení ribonukleasy A konjugované hyaluronidasou a PEG na biologické a protinádorové aktivity (cs)
skos:prefLabel	Effect of hyaluronidase and PEG chain conjugation on the biologic and antitumour activity of RNase A Effect of hyaluronidase and PEG chain conjugation on the biologic and antitumour activity of RNase A (en) Působení ribonukleasy A konjugované hyaluronidasou a PEG na biologické a protinádorové aktivity (cs)
skos:notation	RIV/67985904:_____/04:00100592!RIV/2005/GA0/A21005/N
http://linked.open.../vavai/riv/strany	401;410
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA523/01/0114), Z(AV0Z5045916)
http://linked.open...iv/cisloPeriodika	-
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Matoušek, Josef
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav živočišné fyziologie a genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	561922
http://linked.open...ai/riv/idVysledku	RIV/67985904:_____/04:00100592
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	antitumour;aspermatogenesis;embryotoxicity (en)
http://linked.open.../riv/klicoveSlovo	embryotoxicity antitumour aspermatogenesis
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[1D6B6135E041]
http://linked.open...i/riv/nazevZdroje	Journal of Controlled Release
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Antitumor effects of bovine seminal ribonuclease on animal and human melanoblastoma, neuroblastoma, meduloblastoma and glioblastoma
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	94
http://linked.open...iv/tvurceVysledku	Poučková, P. Matoušek, Josef Škvor, J. Zadinová, M. Souček, J. Hloušková, D.
http://linked.open...n/vavai/riv/zamer	Základní výzkum genetických struktur, fyziologických funkcí a vývojové biologie obratlovců se zaměřením na biomedicínsky, hospodářsky i jinak významné druhy
issn	0168-3659
number of pages	10 (xsd:int)

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