About: Chromosome Condensation in Pig Oocytes: Lack of a requirement for Either cdc2 Kinase or MAP Kinase Activity.

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About: Chromosome Condensation in Pig Oocytes: Lack of a requirement for Either cdc2 Kinase or MAP Kinase Activity. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In this study, butyrolactone I (BL I), a potent and specific inhibitor of cyclin-dependent kinases (cdk), is shown to inhibit germinal vesicle breakdown (GVBD) in pig oocytes. Results suggest that both chromosome condensation and GVBD could occur without activation of cdc2 kinase, whereas an increase in MAP kinase activity may be a requisite for GVBD in pig oocytes in conditions when cdc2 kinase activation is blocked by BL I. In this study, butyrolactone I (BL I), a potent and specific inhibitor of cyclin-dependent kinases (cdk), is shown to inhibit germinal vesicle breakdown (GVBD) in pig oocytes. Results suggest that both chromosome condensation and GVBD could occur without activation of cdc2 kinase, whereas an increase in MAP kinase activity may be a requisite for GVBD in pig oocytes in conditions when cdc2 kinase activation is blocked by BL I. (en)
Title	Chromosome Condensation in Pig Oocytes: Lack of a requirement for Either cdc2 Kinase or MAP Kinase Activity. Chromosome Condensation in Pig Oocytes: Lack of a requirement for Either cdc2 Kinase or MAP Kinase Activity. (en)
skos:prefLabel	Chromosome Condensation in Pig Oocytes: Lack of a requirement for Either cdc2 Kinase or MAP Kinase Activity. Chromosome Condensation in Pig Oocytes: Lack of a requirement for Either cdc2 Kinase or MAP Kinase Activity. (en)
skos:notation	RIV/67985904:_____/02:21023127!RIV/2003/AV0/A21003/N
http://linked.open.../vavai/riv/strany	110;118
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA203/99/1459), P(KSK5052113), Z(AV0Z5045916)
http://linked.open...iv/cisloPeriodika	N/A
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Kalous, Jaroslav Motlík, Jan Kubelka, Michal Anger, Martin
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav živočišné fyziologie a genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	640866
http://linked.open...ai/riv/idVysledku	RIV/67985904:_____/02:21023127
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	GVBD; chromosome condensation; okadaic acid (en)
http://linked.open.../riv/klicoveSlovo	GVBD chromosome condensation okadaic acid
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[2E8468976EEB]
http://linked.open...i/riv/nazevZdroje	Molecular Reproduction and Development
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Structure, expression and interaction of the genome Phosphonate analogues of ATP as potential inhibitors of protein kinases
http://linked.open...UplatneniVysledku	2002
http://linked.open...v/svazekPeriodika	63
http://linked.open...iv/tvurceVysledku	Motlík, Jan Anger, Martin Kalous, Jaroslav Kubelka, Michal Schultz, R. M.
http://linked.open...n/vavai/riv/zamer	Základní výzkum genetických struktur, fyziologických funkcí a vývojové biologie obratlovců se zaměřením na biomedicínsky, hospodářsky i jinak významné druhy
issn	1040-452X
number of pages	9 (xsd:int)

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