About: Streptavidin-enhanced assay for sensitive and specific detection of single nucleotide polymorphism in TP53

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About: Streptavidin-enhanced assay for sensitive and specific detection of single nucleotide polymorphism in TP53 Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	This paper reports an approach to detection of single nucleotide polymorphism based on special amplification assay and surface plasmon resonance (SPR) biosensor technology. In this assay, a part of the target DNA is recognized by a probe coupled with streptavidin-oligonucleotide (SON) complexes ex-situ. The SON-target complex is then detected with the SPR sensor with high specificity and sensitivity. The assay is applied to detection of short analogue of TP53 at levels down to 40 pM. This paper reports an approach to detection of single nucleotide polymorphism based on special amplification assay and surface plasmon resonance (SPR) biosensor technology. In this assay, a part of the target DNA is recognized by a probe coupled with streptavidin-oligonucleotide (SON) complexes ex-situ. The SON-target complex is then detected with the SPR sensor with high specificity and sensitivity. The assay is applied to detection of short analogue of TP53 at levels down to 40 pM. (en)
Title	Streptavidin-enhanced assay for sensitive and specific detection of single nucleotide polymorphism in TP53 Streptavidin-enhanced assay for sensitive and specific detection of single nucleotide polymorphism in TP53 (en)
skos:prefLabel	Streptavidin-enhanced assay for sensitive and specific detection of single nucleotide polymorphism in TP53 Streptavidin-enhanced assay for sensitive and specific detection of single nucleotide polymorphism in TP53 (en)
skos:notation	RIV/67985882:_____/11:00358220!RIV11-MSM-67985882
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA202/09/0193), P(KAN200670701), P(OC09058), Z(AV0Z20670512)
http://linked.open...iv/cisloPeriodika	7
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Homola, Jiří Šípová, Hana Špringer, Tomáš
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav fotoniky a elektroniky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	232602
http://linked.open...ai/riv/idVysledku	RIV/67985882:_____/11:00358220
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Surface Plasmon Resonance; point mutation; amplification (en)
http://linked.open.../riv/klicoveSlovo	Surface Plasmon Resonance point mutation amplification
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[15FAC76C63E3]
http://linked.open...i/riv/nazevZdroje	Analytical and Bioanalytical Chemistry
http://linked.open...in/vavai/riv/obor	JB
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Plasmonic nanostructures and functionalizations for optical affinity biosensors Surface plasmon resonance biosensors and protein arrays for medical diagnostics Formation and dynamics of nucleic acid motifs involved in regulation of gene expression
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	399
http://linked.open...iv/tvurceVysledku	Homola, Jiří Špringer, Tomáš Šípová, Hana
http://linked.open...ain/vavai/riv/wos	000287141700006
http://linked.open...n/vavai/riv/zamer	Materiály, struktury, systémy a signály v elektronice, optoelektronice a fotonice
issn	1618-2642
number of pages	8 (xsd:int)

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