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  • Diagrammatic representation of the feedback mechanisms in gene regulation systems is presented. It affords their exact formulation in terms of topology and transmission functions of the diagram edges. The approach is demonstrated on a system, previously studied by Smolen et al., comprising two genes whose transcription is controlled by activator and repressor proteins mutually competing for binding to the same responsive element of the DNA. Interplay of two corresponding feedback mechanisms is described.
  • Diagrammatic representation of the feedback mechanisms in gene regulation systems is presented. It affords their exact formulation in terms of topology and transmission functions of the diagram edges. The approach is demonstrated on a system, previously studied by Smolen et al., comprising two genes whose transcription is controlled by activator and repressor proteins mutually competing for binding to the same responsive element of the DNA. Interplay of two corresponding feedback mechanisms is described. (en)
  • Je prezentována diagramatická reprezentace zpětnovazebních mechanizmů v genových regulačních soustavách, která umožňuje jejich přesnou formulaci pomocí topologie a přenosových funkcí diagramů. Možnosti přístupu jsou demonstrovány na příkladu dvou genů (který byl studován Smolenem aj.), jejichž transkripce je kontrolována aktivační a represivní bílkovinou, které soutěží o možnost navázání na stejné regulační místo DNA. Je popsána synergie odpovídajících mechanismů kladné a záporné zpětné vazby. (cs)
Title
  • Synergy of feedback mechanisms in gene regulation systems with promoter and repressor transcription factors
  • Synergie zpětnovazebních mechanismů v systémech genové regulace s pozitivními a negativními faktory transkripce (cs)
  • Synergy of feedback mechanisms in gene regulation systems with promoter and repressor transcription factors (en)
skos:prefLabel
  • Synergy of feedback mechanisms in gene regulation systems with promoter and repressor transcription factors
  • Synergie zpětnovazebních mechanismů v systémech genové regulace s pozitivními a negativními faktory transkripce (cs)
  • Synergy of feedback mechanisms in gene regulation systems with promoter and repressor transcription factors (en)
skos:notation
  • RIV/67985882:_____/08:00306409!RIV08-AV0-67985882
http://linked.open.../vavai/riv/strany
  • 38;44
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(AV0Z20670512)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 398682
http://linked.open...ai/riv/idVysledku
  • RIV/67985882:_____/08:00306409
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • biophysics; feedback; signal flow graphs (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • PL - Polská republika
http://linked.open...ontrolniKodProRIV
  • [8D78EE9D049A]
http://linked.open...i/riv/nazevZdroje
  • Central European Journal of Physics
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 6
http://linked.open...iv/tvurceVysledku
  • Šrobár, Fedor
http://linked.open...n/vavai/riv/zamer
issn
  • 1895-1082
number of pages
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