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  • Oleuropein, the major phenolic compound found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects and suppresses the adipocyte differentiation in vitro. Herein, we characterized molecular mechanisms underlying the anti-adipogenic effects of oleuropein on 3T3-L1 cells and adipocytes derived from stromal-vascular fraction of dorsolumbar and gonadal fat dissected from mice. Our data suggest that oleuropein exerts anti-adipogenic effect through direct inhibition of PPARγ transcriptional activity
  • Oleuropein, the major phenolic compound found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects and suppresses the adipocyte differentiation in vitro. Herein, we characterized molecular mechanisms underlying the anti-adipogenic effects of oleuropein on 3T3-L1 cells and adipocytes derived from stromal-vascular fraction of dorsolumbar and gonadal fat dissected from mice. Our data suggest that oleuropein exerts anti-adipogenic effect through direct inhibition of PPARγ transcriptional activity (en)
Title
  • Oleuropein as an inhibitor of peroxisome proliferator-activated receptor gamma
  • Oleuropein as an inhibitor of peroxisome proliferator-activated receptor gamma (en)
skos:prefLabel
  • Oleuropein as an inhibitor of peroxisome proliferator-activated receptor gamma
  • Oleuropein as an inhibitor of peroxisome proliferator-activated receptor gamma (en)
skos:notation
  • RIV/67985823:_____/14:00437821!RIV15-GA0-67985823
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  • I, P(GAP301/11/0226)
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  • 1
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  • 34169
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  • RIV/67985823:_____/14:00437821
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  • oleuropein; adipogenesis; PPARγ; olive oil and leaf extracts; catalase (en)
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  • US - Spojené státy americké
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  • [8A249D82C491]
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  • Genes and Nutrition
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  • 9
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  • Kopecký, Jan
  • Flachs, Pavel
  • Svobodová, Michaela
  • Andreadou, I.
  • Skaltsounis, A.-L.
http://linked.open...ain/vavai/riv/wos
  • 000330936200018
issn
  • 1555-8932
number of pages
http://bibframe.org/vocab/doi
  • 10.1007/s12263-013-0376-0
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