About: Contribution of Ca2+-Dependent Cl- Channels to Norepinephrine-Induced Contraction of Femoral Artery Is Replaced by Increasing EDCF Contribution during Ageing

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About: Contribution of Ca2+-Dependent Cl- Channels to Norepinephrine-Induced Contraction of Femoral Artery Is Replaced by Increasing EDCF Contribution during Ageing Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The activation of calcium-dependent chloride channels during norepinephrine-induced contraction of vascular smooth muscle was suggested to depolarize cell membrane and to increase calcium entry. Hypertension and ageing are associated with altered calcium handling including possible activation of calcium-dependent chloride channels. Our study was aimed to determine calcium -dependent chloride channels contribution to norepinephrine-induced contraction during hypertension and ageing. We have found that contribution of calcium -dependent chloride channels to norepinephrine-induced contraction diminished with age, hypertension development, and/or NO synthesis inhibition The activation of calcium-dependent chloride channels during norepinephrine-induced contraction of vascular smooth muscle was suggested to depolarize cell membrane and to increase calcium entry. Hypertension and ageing are associated with altered calcium handling including possible activation of calcium-dependent chloride channels. Our study was aimed to determine calcium -dependent chloride channels contribution to norepinephrine-induced contraction during hypertension and ageing. We have found that contribution of calcium -dependent chloride channels to norepinephrine-induced contraction diminished with age, hypertension development, and/or NO synthesis inhibition (en)
Title	Contribution of Ca2+-Dependent Cl- Channels to Norepinephrine-Induced Contraction of Femoral Artery Is Replaced by Increasing EDCF Contribution during Ageing Contribution of Ca2+-Dependent Cl- Channels to Norepinephrine-Induced Contraction of Femoral Artery Is Replaced by Increasing EDCF Contribution during Ageing (en)
skos:prefLabel	Contribution of Ca2+-Dependent Cl- Channels to Norepinephrine-Induced Contraction of Femoral Artery Is Replaced by Increasing EDCF Contribution during Ageing Contribution of Ca2+-Dependent Cl- Channels to Norepinephrine-Induced Contraction of Femoral Artery Is Replaced by Increasing EDCF Contribution during Ageing (en)
skos:notation	RIV/67985823:_____/14:00428048!RIV15-GA0-67985823
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(GAP304/12/0259)
http://linked.open...iv/cisloPeriodika	2014
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Líšková, Silvia Karen, Petr Zicha, Josef Behuliak, Michal
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	8820
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/14:00428048
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	calcium-dependent chloride channels; endothelium-derived contracting factor; ageing (en)
http://linked.open.../riv/klicoveSlovo	ageing calcium-dependent chloride channels endothelium-derived contracting factor
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[6711CB378D90]
http://linked.open...i/riv/nazevZdroje	BioMed Research International
http://linked.open...in/vavai/riv/obor	FA
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Mutual interactions of various vasoactive systems, reactive oxygen species and G proteins in experimental hypertension
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	2014
http://linked.open...iv/tvurceVysledku	Petrová, M. Zicha, Josef Karen, Petr Líšková, Silvia Behuliak, Michal
http://linked.open...ain/vavai/riv/wos	000332565500001
issn	2314-6133
number of pages	9 (xsd:int)
http://bibframe.org/vocab/doi	10.1155/2014/289361

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