About: Structural and functional properties of the rat P2X4 purinoreceptor extracellular vestibule during gating     Goto   Sponge   NotDistinct   Permalink

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  • We used cysteine and alanine scanning mutagenesis of the rat P2X4R receptor V47-V61 and K326-N338 sequences to study structural and functional properties of extracellular vestibule during gating. The effect of cadmium on channel gating was stimulatory in the majority of reactive V47-V61 mutants and inhibitory in the majority of reactive K326-N338 mutants, which suggests opposite roles for these sequences in receptor gating
  • We used cysteine and alanine scanning mutagenesis of the rat P2X4R receptor V47-V61 and K326-N338 sequences to study structural and functional properties of extracellular vestibule during gating. The effect of cadmium on channel gating was stimulatory in the majority of reactive V47-V61 mutants and inhibitory in the majority of reactive K326-N338 mutants, which suggests opposite roles for these sequences in receptor gating (en)
Title
  • Structural and functional properties of the rat P2X4 purinoreceptor extracellular vestibule during gating
  • Structural and functional properties of the rat P2X4 purinoreceptor extracellular vestibule during gating (en)
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  • Structural and functional properties of the rat P2X4 purinoreceptor extracellular vestibule during gating
  • Structural and functional properties of the rat P2X4 purinoreceptor extracellular vestibule during gating (en)
skos:notation
  • RIV/67985823:_____/14:00427632!RIV15-GA0-67985823
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  • I, P(ED1.1.00/02.0109), P(GBP304/12/G069)
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  • Jan 29
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  • 47822
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  • RIV/67985823:_____/14:00427632
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  • ATP; cadmium; ion access; purinergic receptors; scanning mutagenesis (en)
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  • CH - Švýcarská konfederace
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  • [4A408BDB6692]
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  • Frontiers in Cellular Neuroscience
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  • 8
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  • Zemková, Hana
  • Stojilkovic, S. S.
  • Rokic, Milos Boro
http://linked.open...ain/vavai/riv/wos
  • 000331053200001
issn
  • 1662-5102
number of pages
http://bibframe.org/vocab/doi
  • 10.3389/fncel.2014.00003
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