About: Susceptibility of rats with altered thyroid status to malignant arrhythmias is primarily related to myocardial levels of connexin-43 and can be partially ameliorated by supplementation with red palm oil

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About: Susceptibility of rats with altered thyroid status to malignant arrhythmias is primarily related to myocardial levels of connexin-43 and can be partially ameliorated by supplementation with red palm oil Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We aimed to explore relationship between myocardial electrical coupling protein connexin-43 (Cx43) and susceptibility of rats with altered thyroid status to malignant arrhythmias and to examine possible beneficial effect of red palm oil (RPO). We conclude that there is an inverse relationship between myocardial Cx43 expression and heart susceptibility of rats with altered thyroid status to VF, whereby PKC.epsilon can also be involved. RPO intake increased threshold for induction of VF in the TH rats, apparently again due to up-regulation of Cx43 and PKC.epsilon We aimed to explore relationship between myocardial electrical coupling protein connexin-43 (Cx43) and susceptibility of rats with altered thyroid status to malignant arrhythmias and to examine possible beneficial effect of red palm oil (RPO). We conclude that there is an inverse relationship between myocardial Cx43 expression and heart susceptibility of rats with altered thyroid status to VF, whereby PKC.epsilon can also be involved. RPO intake increased threshold for induction of VF in the TH rats, apparently again due to up-regulation of Cx43 and PKC.epsilon (en)
Title	Susceptibility of rats with altered thyroid status to malignant arrhythmias is primarily related to myocardial levels of connexin-43 and can be partially ameliorated by supplementation with red palm oil Susceptibility of rats with altered thyroid status to malignant arrhythmias is primarily related to myocardial levels of connexin-43 and can be partially ameliorated by supplementation with red palm oil (en)
skos:prefLabel	Susceptibility of rats with altered thyroid status to malignant arrhythmias is primarily related to myocardial levels of connexin-43 and can be partially ameliorated by supplementation with red palm oil Susceptibility of rats with altered thyroid status to malignant arrhythmias is primarily related to myocardial levels of connexin-43 and can be partially ameliorated by supplementation with red palm oil (en)
skos:notation	RIV/67985823:_____/13:00435701!RIV15-GA0-67985823
http://linked.open...avai/riv/aktivita	I P Z
http://linked.open...avai/riv/aktivity	I, P(7AMB12SK158), P(GA305/09/1228), P(GAP304/12/0259), Z(AV0Z50110509)
http://linked.open...iv/cisloPeriodika	Suppl A
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Kašparová, Dita Soukup, Tomáš Pavelka, Stanislav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	109148
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/13:00435701
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	thyroid hormones; cardiac arrhythmias; connexin-43; PKC.epsilon; red palm oil (en)
http://linked.open.../riv/klicoveSlovo	connexin-43 cardiac arrhythmias PKC.epsilon red palm oil thyroid hormones
http://linked.open...odStatuVydavatele	CA - Kanada
http://linked.open...ontrolniKodProRIV	[8AC756428ADE]
http://linked.open...i/riv/nazevZdroje	Experimental and Clinical Cardiology
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	Cellular and molecular mechanisms of pain transmission at spinal cord level. Mutual interactions of various vasoactive systems, reactive oxygen species and G proteins in experimental hypertension Investigation of the cardioprotection against injury and malignant arrhythmias induced by altered thyroid state.
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	18
http://linked.open...iv/tvurceVysledku	Soukup, Tomáš Žurmanová, J. Kašparová, Dita Pavelka, Stanislav Tribulová, N. Knezl, V. Bačová, B. Beňová, T. Radošinská, J. Vinczenzová, C.
http://linked.open...n/vavai/riv/zamer	Výzkum molekulárních a buněčných základů fyziologických a patofyziologických procesů s cílem objasnit mechanismy vzniku závažných onemocnění člověka
issn	1205-6626
number of pages	6 (xsd:int)

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