About: Stimulation of mitochondrial oxidative capacity in white fat independent of UCP1: A key to lean phenotype     Goto   Sponge   NotDistinct   Permalink

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  • In this review, we better characterised the intracellular handles, which could be targeted to improve metabolic properties of adipocytes in WAT. New combination treatment strategies may be designed including naturally occurring micronutrients like omega 3 and plant polyphenols, reduced calorie intake, and pharmacological modulators of key signalling pathways in fat cells. Involvement of the mutual interactions between adipocytes and immune cells contained in WAT may be essential for the induction of lipid catabolism in white adipocytes and the lean phenotype
  • In this review, we better characterised the intracellular handles, which could be targeted to improve metabolic properties of adipocytes in WAT. New combination treatment strategies may be designed including naturally occurring micronutrients like omega 3 and plant polyphenols, reduced calorie intake, and pharmacological modulators of key signalling pathways in fat cells. Involvement of the mutual interactions between adipocytes and immune cells contained in WAT may be essential for the induction of lipid catabolism in white adipocytes and the lean phenotype (en)
Title
  • Stimulation of mitochondrial oxidative capacity in white fat independent of UCP1: A key to lean phenotype
  • Stimulation of mitochondrial oxidative capacity in white fat independent of UCP1: A key to lean phenotype (en)
skos:prefLabel
  • Stimulation of mitochondrial oxidative capacity in white fat independent of UCP1: A key to lean phenotype
  • Stimulation of mitochondrial oxidative capacity in white fat independent of UCP1: A key to lean phenotype (en)
skos:notation
  • RIV/67985823:_____/13:00392288!RIV14-MSM-67985823
http://linked.open...avai/riv/aktivita
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  • I, P(7E12073), P(GAP301/11/0226)
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  • 5
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  • 107997
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  • RIV/67985823:_____/13:00392288
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  • fatty acid re-esterification; futile substrate cycle; PPAR gamma; adipose tissue; lipid mediator; obesity (en)
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  • NL - Nizozemsko
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  • [5B6D9AF774C9]
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  • Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids
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  • 1831
http://linked.open...iv/tvurceVysledku
  • Kopecký, Jan
  • Flachs, Pavel
  • Kuda, Ondřej
  • Rossmeisl, Martin
http://linked.open...ain/vavai/riv/wos
  • 000317996000011
issn
  • 1388-1981
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.bbalip.2013.02.003
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