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rdf:type
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Description
| - The brain tissue has the high rate of oxidative metabolic activity, high concentration of polyunsaturated fatty acids in membrane lipids, presence of iron and low capacity of antioxidant enzymes, which makes the brain very susceptible to reactive oxygen species action and lipid peroxidation formation. Membranes of brain cortex show a higher production of thiobarbituric acid-reactive substances (TBARS) in prooxidant system (ADP-Fe3+/NADPH) then membranes from the heart or kidney. The experimental model of short-term hypoxia shows remarkable increase in TBARS in four different parts of the rat brain (cortex, subcortical structures, cerebellum and medulla oblongata) during the postnatal development of Wistar rats of both sexes. Young rats and males are more sensitive to oxygen changes than adult rats and female, respectively. Rats pretreated with L-carnitine (and its derivatives) have lower TBARS levels after exposure to hypobaric hypoxia
- The brain tissue has the high rate of oxidative metabolic activity, high concentration of polyunsaturated fatty acids in membrane lipids, presence of iron and low capacity of antioxidant enzymes, which makes the brain very susceptible to reactive oxygen species action and lipid peroxidation formation. Membranes of brain cortex show a higher production of thiobarbituric acid-reactive substances (TBARS) in prooxidant system (ADP-Fe3+/NADPH) then membranes from the heart or kidney. The experimental model of short-term hypoxia shows remarkable increase in TBARS in four different parts of the rat brain (cortex, subcortical structures, cerebellum and medulla oblongata) during the postnatal development of Wistar rats of both sexes. Young rats and males are more sensitive to oxygen changes than adult rats and female, respectively. Rats pretreated with L-carnitine (and its derivatives) have lower TBARS levels after exposure to hypobaric hypoxia (en)
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Title
| - Hypoxia-induced lipid peroxidation in the brain during postnatal ontogenesis
- Hypoxia-induced lipid peroxidation in the brain during postnatal ontogenesis (en)
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skos:prefLabel
| - Hypoxia-induced lipid peroxidation in the brain during postnatal ontogenesis
- Hypoxia-induced lipid peroxidation in the brain during postnatal ontogenesis (en)
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skos:notation
| - RIV/67985823:_____/12:00380085!RIV13-GA0-67985823
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - I, P(1M0510), P(GAP304/12/0259), Z(AV0Z50110509)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/67985823:_____/12:00380085
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - hypobaric hypoxia; reactive oxygen species (ROS); polyunsaturated fatty acids; Na; K-ATPase; catalase; L-carnitine (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Rauchová, Hana
- Vokurková, Martina
- Koudelová, J.
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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