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Description
  • The present findings provide the evidence of oxidative stress in brain of immature rats during seizures induced by DL-homocysteic acid.The enhanced O-2 center dot(-)production was significantly attenuated or completely prevented by substances providing an anticonvulsant effect and by selected SOD mimetics.The increased O-2 center dot(-)generation precedes neuronal degeneration and may thus play a causative role in neuronal injury
  • The present findings provide the evidence of oxidative stress in brain of immature rats during seizures induced by DL-homocysteic acid.The enhanced O-2 center dot(-)production was significantly attenuated or completely prevented by substances providing an anticonvulsant effect and by selected SOD mimetics.The increased O-2 center dot(-)generation precedes neuronal degeneration and may thus play a causative role in neuronal injury (en)
Title
  • Brain superoxide anion formation in immature rats during seizures: Protection by selected compounds
  • Brain superoxide anion formation in immature rats during seizures: Protection by selected compounds (en)
skos:prefLabel
  • Brain superoxide anion formation in immature rats during seizures: Protection by selected compounds
  • Brain superoxide anion formation in immature rats during seizures: Protection by selected compounds (en)
skos:notation
  • RIV/67985823:_____/12:00376883!RIV13-GA0-67985823
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA309/08/0292), P(GAP303/10/0999), Z(AV0Z50110509)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...dnocenehoVysledku
  • 125464
http://linked.open...ai/riv/idVysledku
  • RIV/67985823:_____/12:00376883
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • immature rats; DL-homocysteic acid-induced seizures; superoxide anion; SOD mimetics; protection; Fluoro-Jade B staining; brain damage (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [71134CFBC9A0]
http://linked.open...i/riv/nazevZdroje
  • Experimental Neurology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 233
http://linked.open...iv/tvurceVysledku
  • Otáhal, Jakub
  • Druga, Rastislav
  • Folbergrová, Jaroslava
http://linked.open...ain/vavai/riv/wos
  • 000300123900047
http://linked.open...n/vavai/riv/zamer
issn
  • 0014-4886
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.expneurol.2011.11.009
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