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Description
| - We examined whether the development of neurogenic pulmonary edema (NPE) in rats with balloon compression of spinal cord is a consequence of rapid activation of spinal pathways leading to sympathetic venoconstriction, blood pressure rise, and reflex bradycardia. We demonstrated that considerable activation of thoracic spinal pathways, followed by marked catecholamine secretion, play a major role in the development of NPE in spinal cord-injured rats. Enhanced α-adrenergic nifedipine-sensitive vasoconstriction is responsible for observed blood pressure changes, subsequent baroreflex bradycardia, and blood volume redistribution, which represent major pathogenetic mechanisms of NPE development
- We examined whether the development of neurogenic pulmonary edema (NPE) in rats with balloon compression of spinal cord is a consequence of rapid activation of spinal pathways leading to sympathetic venoconstriction, blood pressure rise, and reflex bradycardia. We demonstrated that considerable activation of thoracic spinal pathways, followed by marked catecholamine secretion, play a major role in the development of NPE in spinal cord-injured rats. Enhanced α-adrenergic nifedipine-sensitive vasoconstriction is responsible for observed blood pressure changes, subsequent baroreflex bradycardia, and blood volume redistribution, which represent major pathogenetic mechanisms of NPE development (en)
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Title
| - The role of sympathetic nervous system in the development of neurogenic pulmonary edema in spinal cord-injured rats
- The role of sympathetic nervous system in the development of neurogenic pulmonary edema in spinal cord-injured rats (en)
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skos:prefLabel
| - The role of sympathetic nervous system in the development of neurogenic pulmonary edema in spinal cord-injured rats
- The role of sympathetic nervous system in the development of neurogenic pulmonary edema in spinal cord-injured rats (en)
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skos:notation
| - RIV/67985823:_____/12:00376805!RIV13-GA0-67985823
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(1M0510), P(GA305/08/0139), P(IAA500110902), V, Z(AV0Z50110509)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/67985823:_____/12:00376805
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - neurogenic pulmonary edema; sympathetic nervous system; baroreflex (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Journal of Applied Physiology
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Kuneš, Jaroslav
- Zicha, Josef
- Šedý, Jiří
- Nedvídková, J.
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://bibframe.org/vocab/doi
| - 10.1152/japplphysiol.00574.2011
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