About: The role of sympathetic nervous system in the development of neurogenic pulmonary edema in spinal cord-injured rats

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About: The role of sympathetic nervous system in the development of neurogenic pulmonary edema in spinal cord-injured rats Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We examined whether the development of neurogenic pulmonary edema (NPE) in rats with balloon compression of spinal cord is a consequence of rapid activation of spinal pathways leading to sympathetic venoconstriction, blood pressure rise, and reflex bradycardia. We demonstrated that considerable activation of thoracic spinal pathways, followed by marked catecholamine secretion, play a major role in the development of NPE in spinal cord-injured rats. Enhanced α-adrenergic nifedipine-sensitive vasoconstriction is responsible for observed blood pressure changes, subsequent baroreflex bradycardia, and blood volume redistribution, which represent major pathogenetic mechanisms of NPE development We examined whether the development of neurogenic pulmonary edema (NPE) in rats with balloon compression of spinal cord is a consequence of rapid activation of spinal pathways leading to sympathetic venoconstriction, blood pressure rise, and reflex bradycardia. We demonstrated that considerable activation of thoracic spinal pathways, followed by marked catecholamine secretion, play a major role in the development of NPE in spinal cord-injured rats. Enhanced α-adrenergic nifedipine-sensitive vasoconstriction is responsible for observed blood pressure changes, subsequent baroreflex bradycardia, and blood volume redistribution, which represent major pathogenetic mechanisms of NPE development (en)
Title	The role of sympathetic nervous system in the development of neurogenic pulmonary edema in spinal cord-injured rats The role of sympathetic nervous system in the development of neurogenic pulmonary edema in spinal cord-injured rats (en)
skos:prefLabel	The role of sympathetic nervous system in the development of neurogenic pulmonary edema in spinal cord-injured rats The role of sympathetic nervous system in the development of neurogenic pulmonary edema in spinal cord-injured rats (en)
skos:notation	RIV/67985823:_____/12:00376805!RIV13-GA0-67985823
http://linked.open...avai/riv/aktivita	P V Z
http://linked.open...avai/riv/aktivity	P(1M0510), P(GA305/08/0139), P(IAA500110902), V, Z(AV0Z50110509)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Zicha, Josef Kuneš, Jaroslav Šedý, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	166066
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/12:00376805
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	neurogenic pulmonary edema; sympathetic nervous system; baroreflex (en)
http://linked.open.../riv/klicoveSlovo	baroreflex sympathetic nervous system neurogenic pulmonary edema
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[BD89D8D5EC90]
http://linked.open...i/riv/nazevZdroje	Journal of Applied Physiology
http://linked.open...in/vavai/riv/obor	FA
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Altered regulation of vasoactive system balance in experimental hypertension Centre for cardiovascular research Neurohumoral control of calcium influx: nifedipine-sensitive component of blood pressure in experimental hypertension
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	112
http://linked.open...iv/tvurceVysledku	Kuneš, Jaroslav Zicha, Josef Šedý, Jiří Nedvídková, J.
http://linked.open...ain/vavai/riv/wos	000298403700001
http://linked.open...n/vavai/riv/zamer	Výzkum molekulárních a buněčných základů fyziologických a patofyziologických procesů s cílem objasnit mechanismy vzniku závažných onemocnění člověka
issn	8750-7587
number of pages	8 (xsd:int)
http://bibframe.org/vocab/doi	10.1152/japplphysiol.00574.2011

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