About: Dual effect of lobeline on alpha 4 beta 2 rat neuronal nicotinic receptors     Goto   Sponge   NotDistinct   Permalink

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  • The effect of lobeline on rat alpha 4 beta 2 nicotinic receptors expressed in COS cells was studied using the patch-clamp technique. We found that the effect of lobeline is complex and varies with applied concentration and the application scheme. The causes of the variable lobeline manifestation (potentiation, inhibition) are different binding and unbinding rates and differences in the affinity of lobeline to individual functional states of nicotinic receptors
  • The effect of lobeline on rat alpha 4 beta 2 nicotinic receptors expressed in COS cells was studied using the patch-clamp technique. We found that the effect of lobeline is complex and varies with applied concentration and the application scheme. The causes of the variable lobeline manifestation (potentiation, inhibition) are different binding and unbinding rates and differences in the affinity of lobeline to individual functional states of nicotinic receptors (en)
Title
  • Dual effect of lobeline on alpha 4 beta 2 rat neuronal nicotinic receptors
  • Dual effect of lobeline on alpha 4 beta 2 rat neuronal nicotinic receptors (en)
skos:prefLabel
  • Dual effect of lobeline on alpha 4 beta 2 rat neuronal nicotinic receptors
  • Dual effect of lobeline on alpha 4 beta 2 rat neuronal nicotinic receptors (en)
skos:notation
  • RIV/67985823:_____/11:00372065!RIV12-AV0-67985823
http://linked.open...avai/riv/aktivita
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  • I, P(GA202/09/0806), P(IAA500110905), P(LC554), Z(AV0Z50110509)
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  • 2-3
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  • 195544
http://linked.open...ai/riv/idVysledku
  • RIV/67985823:_____/11:00372065
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  • lobeline; nicotinic acetylcholine receptor (en)
http://linked.open.../riv/klicoveSlovo
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  • NL - Nizozemsko
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  • [70E4864E4E61]
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  • European Journal of Pharmacology
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  • 658
http://linked.open...iv/tvurceVysledku
  • Vyskočil, František
  • Adámek, S.
  • Kaniaková, Martina
  • Krůšek, Jan
  • Lindovský, Jiří
http://linked.open...ain/vavai/riv/wos
  • 000290010500008
http://linked.open...n/vavai/riv/zamer
issn
  • 0014-2999
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.ejphar.2011.02.012
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