About: Structural Basis for the 14-3-3 Protein-dependent Inhibition of the Regulator of G Protein Signaling 3 (RGS3) Function

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About: Structural Basis for the 14-3-3 Protein-dependent Inhibition of the Regulator of G Protein Signaling 3 (RGS3) Function Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Background: The 14-3-3 protein binds to and regulates the function of the regulator of G protein signaling 3 (RGS3). Results: The 14-3-3 binding affects the structure of the G.alpha. interaction portion of RGS3. Conclusion: The 14-3-3 protein blocks the interaction between the RGS3 and the G.alpha.. Significance: This might explain the inhibitory function of 14-3-3 in the regulation of RGS3 Background: The 14-3-3 protein binds to and regulates the function of the regulator of G protein signaling 3 (RGS3). Results: The 14-3-3 binding affects the structure of the G.alpha. interaction portion of RGS3. Conclusion: The 14-3-3 protein blocks the interaction between the RGS3 and the G.alpha.. Significance: This might explain the inhibitory function of 14-3-3 in the regulation of RGS3 (en)
Title	Structural Basis for the 14-3-3 Protein-dependent Inhibition of the Regulator of G Protein Signaling 3 (RGS3) Function Structural Basis for the 14-3-3 Protein-dependent Inhibition of the Regulator of G Protein Signaling 3 (RGS3) Function (en)
skos:prefLabel	Structural Basis for the 14-3-3 Protein-dependent Inhibition of the Regulator of G Protein Signaling 3 (RGS3) Function Structural Basis for the 14-3-3 Protein-dependent Inhibition of the Regulator of G Protein Signaling 3 (RGS3) Function (en)
skos:notation	RIV/67985823:_____/11:00370392!RIV12-AV0-67985823
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(GAP207/10/1040), P(GAP305/11/0708), P(IAA501110801), P(LC554), S, Z(AV0Z50110509), Z(AV0Z50200510), Z(MSM0021620835), Z(MSM0021620857)
http://linked.open...iv/cisloPeriodika	50
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Obšilová, Veronika
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	232732
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/11:00370392
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	RGS3; 14-3-3; inhibition; signaling; SAXS; fluorescence (en)
http://linked.open.../riv/klicoveSlovo	SAXS RGS3 fluorescence inhibition signaling 14-3-3
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[6DB84358E4EE]
http://linked.open...i/riv/nazevZdroje	Journal of Biological Chemistry
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Role of the 14-3-3 protein in the regulation of phosducin function Study of the interaction between 14-3-3 protein and regulator of G protein signaling RGS3. Neuroscience Centre Analysis of protein complexes of killer cell receptors using chemical cross-linking, surface labeling, isotope exchange, mass spectrometry and NMR.
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	286
http://linked.open...iv/tvurceVysledku	Man, Petr Novák, Petr Herman, P. Obšil, T. Obšilová, Veronika Večeř, J. Řežábková, L.
http://linked.open...ain/vavai/riv/wos	000298351300072
http://linked.open...n/vavai/riv/zamer	Výzkum molekulárních a buněčných základů fyziologických a patofyziologických procesů s cílem objasnit mechanismy vzniku závažných onemocnění člověka Microorganisms in Research and Biotechnology Fyzika molekulárních, makromolekulárních a biologických systémů Nové molekulární systémy pro pokročilé aplikace prospěšné pro zdraví a šetrné k životnímu prostředí
issn	0021-9258
number of pages	10 (xsd:int)
http://bibframe.org/vocab/doi	10.1074/jbc.M111.303339

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