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rdf:type
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Description
| - In this review authors posit following hypothesis: Independently of whether malignant tumors are initiated by a fundamental reprogramming of gene expression or seeded by stem cells, waves of gene expression that promote metabolic changes occur during carcinogenesis, beginning with oncogene-mediated changes, followed by hypoxia-induced factor (HIF)-mediated gene expression, both resulting in the highly glycolytic Warburg phenotype and suppression of mitochondrial biogenesis
- In this review authors posit following hypothesis: Independently of whether malignant tumors are initiated by a fundamental reprogramming of gene expression or seeded by stem cells, waves of gene expression that promote metabolic changes occur during carcinogenesis, beginning with oncogene-mediated changes, followed by hypoxia-induced factor (HIF)-mediated gene expression, both resulting in the highly glycolytic Warburg phenotype and suppression of mitochondrial biogenesis (en)
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Title
| - Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells
- Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells (en)
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skos:prefLabel
| - Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells
- Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells (en)
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skos:notation
| - RIV/67985823:_____/11:00370173!RIV12-MZ0-67985823
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(IAA500110701), P(ME09029), P(NR7778), Z(AV0Z50110509)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
| |
http://linked.open...dnocenehoVysledku
| |
http://linked.open...ai/riv/idVysledku
| - RIV/67985823:_____/11:00370173
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - metabolic changes; mitochondria; carcinogenesis (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - International Journal of Biochemistry and Cell Biology
|
http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
| |
http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
| |
http://linked.open...v/svazekPeriodika
| |
http://linked.open...iv/tvurceVysledku
| - Ježek, Petr
- Smolková, Katarína
- Bellance, N.
- Benard, G.
- Plecitá-Hlavatá, Lydie
- Rossignol, R.
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://bibframe.org/vocab/doi
| - 10.1016/j.biocel.2010.05.003
|