About: Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In this review authors posit following hypothesis: Independently of whether malignant tumors are initiated by a fundamental reprogramming of gene expression or seeded by stem cells, waves of gene expression that promote metabolic changes occur during carcinogenesis, beginning with oncogene-mediated changes, followed by hypoxia-induced factor (HIF)-mediated gene expression, both resulting in the highly glycolytic Warburg phenotype and suppression of mitochondrial biogenesis In this review authors posit following hypothesis: Independently of whether malignant tumors are initiated by a fundamental reprogramming of gene expression or seeded by stem cells, waves of gene expression that promote metabolic changes occur during carcinogenesis, beginning with oncogene-mediated changes, followed by hypoxia-induced factor (HIF)-mediated gene expression, both resulting in the highly glycolytic Warburg phenotype and suppression of mitochondrial biogenesis (en)
Title	Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells (en)
skos:prefLabel	Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells (en)
skos:notation	RIV/67985823:_____/11:00370173!RIV12-MZ0-67985823
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(IAA500110701), P(ME09029), P(NR7778), Z(AV0Z50110509)
http://linked.open...iv/cisloPeriodika	7
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Ježek, Petr Smolková, Katarína Plecitá-Hlavatá, Lydie
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	241562
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/11:00370173
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	metabolic changes; mitochondria; carcinogenesis (en)
http://linked.open.../riv/klicoveSlovo	metabolic changes mitochondria carcinogenesis
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[685ED925F4C7]
http://linked.open...i/riv/nazevZdroje	International Journal of Biochemistry and Cell Biology
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Imaging of mitochondrial substructure by 3D high resolution microscopy Antioxidant role vs. mitochondrial morphology and their impairment during oxidative stress in diabetic tissues and ischemic heart Complex liposomal forms of photosentitizers for experimental photodynamic therapy of tumors
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	43
http://linked.open...iv/tvurceVysledku	Ježek, Petr Smolková, Katarína Bellance, N. Benard, G. Plecitá-Hlavatá, Lydie Rossignol, R.
http://linked.open...ain/vavai/riv/wos	000292362200003
http://linked.open...n/vavai/riv/zamer	Výzkum molekulárních a buněčných základů fyziologických a patofyziologických procesů s cílem objasnit mechanismy vzniku závažných onemocnění člověka
issn	1357-2725
number of pages	19 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.biocel.2010.05.003

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 48 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software