About: Up-regulation of adenylylcyclases I and II induced by long-term adaptation of rats to morphine fades away 20 days after morphine withdrawal

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About: Up-regulation of adenylylcyclases I and II induced by long-term adaptation of rats to morphine fades away 20 days after morphine withdrawal Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We assume that the specific increase in expression level of ACI and ACII in brain cortex of morphine-adapted rats proceeds as a compensatory, homeostatic response to prolonged exposure to inhibitory drug, morphine. Our findings demonstrate that the dramatic and specific change of the crucial component of the opioid receptor cascade in brain cortex, manifested as an increase in PM level of ACI and II, is reversible We assume that the specific increase in expression level of ACI and ACII in brain cortex of morphine-adapted rats proceeds as a compensatory, homeostatic response to prolonged exposure to inhibitory drug, morphine. Our findings demonstrate that the dramatic and specific change of the crucial component of the opioid receptor cascade in brain cortex, manifested as an increase in PM level of ACI and II, is reversible (en)
Title	Up-regulation of adenylylcyclases I and II induced by long-term adaptation of rats to morphine fades away 20 days after morphine withdrawal Up-regulation of adenylylcyclases I and II induced by long-term adaptation of rats to morphine fades away 20 days after morphine withdrawal (en)
skos:prefLabel	Up-regulation of adenylylcyclases I and II induced by long-term adaptation of rats to morphine fades away 20 days after morphine withdrawal Up-regulation of adenylylcyclases I and II induced by long-term adaptation of rats to morphine fades away 20 days after morphine withdrawal (en)
skos:notation	RIV/67985823:_____/11:00369475!RIV12-AV0-67985823
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GD305/08/H037), P(LC06063), P(LC554), Z(AV0Z50110509)
http://linked.open...iv/cisloPeriodika	12
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Svoboda, Petr Vošahlíková, Miroslava Roubalová, Lenka Dlouhá, Kateřina Ujčíková, Hana Kagan, Dmytro
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	236997
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/11:00369475
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	morphine; long-term adaptation; adenylyl cyclase isoforms I–IX; forebrain cortex; isolated plasma membranes (en)
http://linked.open.../riv/klicoveSlovo	adenylyl cyclase isoforms I–IX forebrain cortex isolated plasma membranes long-term adaptation morphine
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[91857959F23E]
http://linked.open...i/riv/nazevZdroje	Biochimica et Biophysica Acta. General Subjects
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Physiology of animal cell (2) Flurescence microscopy in biological and medical research Neuroscience Centre
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	1810
http://linked.open...iv/tvurceVysledku	Svoboda, Petr Kagan, Dmytro Dlouhá, Kateřina Roubalová, Lenka Vošahlíková, Miroslava Ujčíková, Hana
http://linked.open...ain/vavai/riv/wos	000297885300011
http://linked.open...n/vavai/riv/zamer	Výzkum molekulárních a buněčných základů fyziologických a patofyziologických procesů s cílem objasnit mechanismy vzniku závažných onemocnění člověka
issn	0304-4165
number of pages	10 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.bbagen.2011.09.017

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