About: Role of FAT/CD36 in novel PKC isoform activation in heart of spontaneously hypertensive rats

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About: Role of FAT/CD36 in novel PKC isoform activation in heart of spontaneously hypertensive rats Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Searching for a possible role of novel protein kinase C (nPKC) in heart with disrupted energy balance, we compared the insulin-resistant spontaneously hypertensive rats (SHR), which carry a nonfunctional variant of the fatty acid transporter FAT/CD36, with the less insulin-resistant congenic strain SHR-4 that is genetically identical except for a segment on chromosome 4 including a wild-type gene for a functional FAT/CD36. Our results demonstrate that reduced insulin resistance in SHR-4 rats is associated with the insulin signaling pathway involving nPKCs Searching for a possible role of novel protein kinase C (nPKC) in heart with disrupted energy balance, we compared the insulin-resistant spontaneously hypertensive rats (SHR), which carry a nonfunctional variant of the fatty acid transporter FAT/CD36, with the less insulin-resistant congenic strain SHR-4 that is genetically identical except for a segment on chromosome 4 including a wild-type gene for a functional FAT/CD36. Our results demonstrate that reduced insulin resistance in SHR-4 rats is associated with the insulin signaling pathway involving nPKCs (en)
Title	Role of FAT/CD36 in novel PKC isoform activation in heart of spontaneously hypertensive rats Role of FAT/CD36 in novel PKC isoform activation in heart of spontaneously hypertensive rats (en)
skos:prefLabel	Role of FAT/CD36 in novel PKC isoform activation in heart of spontaneously hypertensive rats Role of FAT/CD36 in novel PKC isoform activation in heart of spontaneously hypertensive rats (en)
skos:notation	RIV/67985823:_____/11:00365731!RIV12-AV0-67985823
http://linked.open...avai/riv/aktivita	P S V Z
http://linked.open...avai/riv/aktivity	P(GD305/08/H037), P(ME08006), S, V, Z(AV0Z50110509), Z(MSM0021620858)
http://linked.open...iv/cisloPeriodika	1-2
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Pravenec, Michal
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	227444
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/11:00365731
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	CD36; novel PKC; spontaneously hypertensive rat; insulin resistance (en)
http://linked.open.../riv/klicoveSlovo	spontaneously hypertensive rat CD36 novel PKC insulin resistance
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[FD641B70E6EB]
http://linked.open...i/riv/nazevZdroje	Molecular and Cellular Biochemistry
http://linked.open...in/vavai/riv/obor	FB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Physiology of animal cell (2) Genetic and correlation analyses of ectopic fat accumulation and adipose tissue oxidative/inflammatory processes and their role in the pathogenesis of insulin resistance
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	357
http://linked.open...iv/tvurceVysledku	Kazdová, L. Marková, I. Pravenec, Michal Novák, F. Nováková, O. Burianová, J. Klevstig, M. J.
http://linked.open...ain/vavai/riv/wos	000295941500018
http://linked.open...n/vavai/riv/zamer	Výzkum molekulárních a buněčných základů fyziologických a patofyziologických procesů s cílem objasnit mechanismy vzniku závažných onemocnění člověka Signaling and cellular response mechanisms
issn	0300-8177
number of pages	7 (xsd:int)
http://bibframe.org/vocab/doi	10.1007/s11010-011-0886-2

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