About: Effects of Human C-Reactive Protein on Pathogenesis of Features of the Metabolic Syndrome

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About: Effects of Human C-Reactive Protein on Pathogenesis of Features of the Metabolic Syndrome Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We sought to investigate whether increased levels of human CRP, per se, can promote increases in blood pressure and disturbances in glucose and lipid metabolism characteristic of the metabolic syndrome. To accomplish this goal, we transgenically expressed human CRP in the spontaneously hypertensive rat (SHR) and found that that increased CRP is more than just a marker of inflammation and can directly promote multiple features of the metabolic syndrome We sought to investigate whether increased levels of human CRP, per se, can promote increases in blood pressure and disturbances in glucose and lipid metabolism characteristic of the metabolic syndrome. To accomplish this goal, we transgenically expressed human CRP in the spontaneously hypertensive rat (SHR) and found that that increased CRP is more than just a marker of inflammation and can directly promote multiple features of the metabolic syndrome (en)
Title	Effects of Human C-Reactive Protein on Pathogenesis of Features of the Metabolic Syndrome Effects of Human C-Reactive Protein on Pathogenesis of Features of the Metabolic Syndrome (en)
skos:prefLabel	Effects of Human C-Reactive Protein on Pathogenesis of Features of the Metabolic Syndrome Effects of Human C-Reactive Protein on Pathogenesis of Features of the Metabolic Syndrome (en)
skos:notation	RIV/67985823:_____/11:00358902!RIV12-MZ0-67985823
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0520), P(GAP301/10/0290), P(GAP303/10/0505), P(IAA500110805), P(ME08006), P(NS9757), P(NS9759), Z(AV0Z50110509), Z(MSM6046070901)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Šilhavý, Jan Zídek, Václav Mlejnek, Petr Šimáková, Miroslava Landa, Vladimír Pravenec, Michal
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	196640
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/11:00358902
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	C-reactive protein; metabolic syndrome; transgenic rat (en)
http://linked.open.../riv/klicoveSlovo	C-reactive protein metabolic syndrome transgenic rat
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[F63C631A2FA3]
http://linked.open...i/riv/nazevZdroje	Hypertension
http://linked.open...in/vavai/riv/obor	FB
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	13 (xsd:int)
http://linked.open...vavai/riv/projekt	Center for Applied Genomics Analysis of mechanisms of adipokine autocrine effects on glucose and lipid metabolism Genetic and correlation analyses of ectopic fat accumulation and adipose tissue oxidative/inflammatory processes and their role in the pathogenesis of insulin resistance The role of C reactive protein in the pathogenesis of metabolic syndrome: nutritional and pharmacological interventions Genetic causes of mitochondrial diseases due to deficiency of ATP synthase Integrated microRNA, mRNA expression profiling, linkage and correlation analyses for identification of genes underlying complex traits Analysis of metabolic effects of telmisartan mediated by selective; PPARgamma modulation
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	57
http://linked.open...iv/tvurceVysledku	Kazdová, L. Kurtz, T. W. Landa, Vladimír Mlejnek, Petr Pravenec, Michal Wang, J. Zídek, Václav Šimáková, Miroslava Fan, J. Kajiya, T. Malínská, H. Oliyarnyk, O. Šilhavý, Jan
http://linked.open...ain/vavai/riv/wos	000288434600019
http://linked.open...n/vavai/riv/zamer	Výzkum molekulárních a buněčných základů fyziologických a patofyziologických procesů s cílem objasnit mechanismy vzniku závažných onemocnění člověka Setrvalé zemědělství, kvalita zemědělské produkce, krajinné a přírodní zdroje.
issn	0194-911X
number of pages	7 (xsd:int)
http://bibframe.org/vocab/doi	10.1161/HYPERTENSIONAHA.110.164350

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