About: Influence of calcium-dependent potassium channel blockade and nitric oxide inhibition on norepinephrine-induced contractions in two forms of genetic hypertension     Goto   Sponge   NotDistinct   Permalink

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  • The activation of Ca2+-dependent K+ channels (BKCa) leads to the attenuation of vascular contraction. Our study aimed to evaluate BKCa influence on norepinephrine (NE)-induced femoral artery contraction in two forms of genetic hypertension. NO-dependent attenuation of NE-induced contractions was greater in SHR than HTG or Wistar vessels, whereas large conductance Ca2+-dependent K+ channels may play a greater role in modulating vascular contraction in the severe form of hypertension
  • The activation of Ca2+-dependent K+ channels (BKCa) leads to the attenuation of vascular contraction. Our study aimed to evaluate BKCa influence on norepinephrine (NE)-induced femoral artery contraction in two forms of genetic hypertension. NO-dependent attenuation of NE-induced contractions was greater in SHR than HTG or Wistar vessels, whereas large conductance Ca2+-dependent K+ channels may play a greater role in modulating vascular contraction in the severe form of hypertension (en)
Title
  • Influence of calcium-dependent potassium channel blockade and nitric oxide inhibition on norepinephrine-induced contractions in two forms of genetic hypertension
  • Influence of calcium-dependent potassium channel blockade and nitric oxide inhibition on norepinephrine-induced contractions in two forms of genetic hypertension (en)
skos:prefLabel
  • Influence of calcium-dependent potassium channel blockade and nitric oxide inhibition on norepinephrine-induced contractions in two forms of genetic hypertension
  • Influence of calcium-dependent potassium channel blockade and nitric oxide inhibition on norepinephrine-induced contractions in two forms of genetic hypertension (en)
skos:notation
  • RIV/67985823:_____/10:00345854!RIV11-AV0-67985823
http://linked.open...avai/riv/aktivita
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  • P(IAA500110902), Z(AV0Z50110509)
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  • 3
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  • 263562
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  • RIV/67985823:_____/10:00345854
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  • potassium channels; nitric oxide; norepinephrine (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [1666EBEB2FB2]
http://linked.open...i/riv/nazevZdroje
  • Journal of the American Society of Hypertension
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  • 4
http://linked.open...iv/tvurceVysledku
  • Kuneš, Jaroslav
  • Petrová, M.
  • Zicha, Josef
  • Karen, Petr
  • Líšková, Silvia
http://linked.open...ain/vavai/riv/wos
  • 278115200004
http://linked.open...n/vavai/riv/zamer
issn
  • 1933-1711
number of pages
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