About: Effect of melatonin, captopril, spironolactone and simvastatin on blood pressure and left ventricular remodelling in spontaneously hypertensive rats     Goto   Sponge   NotDistinct   Permalink

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  • Melatonin was shown to reduce blood pressure and oxidative load as well as to increase nitric oxide availability. It was investigated whether melatonin can reverse left ventricular remodeling in spontaneously hypertensive rats and to compare its protective effect with captopril, spironolactone, or simvastatin. It is concluded that although melatonin, in comparison with captopril, did not reverse left ventricle hypertrophy, it reversed left ventricular fibrosis due to its prominent antioxidative effect
  • Melatonin was shown to reduce blood pressure and oxidative load as well as to increase nitric oxide availability. It was investigated whether melatonin can reverse left ventricular remodeling in spontaneously hypertensive rats and to compare its protective effect with captopril, spironolactone, or simvastatin. It is concluded that although melatonin, in comparison with captopril, did not reverse left ventricle hypertrophy, it reversed left ventricular fibrosis due to its prominent antioxidative effect (en)
Title
  • Effect of melatonin, captopril, spironolactone and simvastatin on blood pressure and left ventricular remodelling in spontaneously hypertensive rats
  • Effect of melatonin, captopril, spironolactone and simvastatin on blood pressure and left ventricular remodelling in spontaneously hypertensive rats (en)
skos:prefLabel
  • Effect of melatonin, captopril, spironolactone and simvastatin on blood pressure and left ventricular remodelling in spontaneously hypertensive rats
  • Effect of melatonin, captopril, spironolactone and simvastatin on blood pressure and left ventricular remodelling in spontaneously hypertensive rats (en)
skos:notation
  • RIV/67985823:_____/09:00330737!RIV10-AV0-67985823
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA305/09/0336), Z(AV0Z50110509), Z(MSM0021620820)
http://linked.open...iv/cisloPeriodika
  • Suppl.6
http://linked.open...vai/riv/dodaniDat
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  • 312165
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  • RIV/67985823:_____/09:00330737
http://linked.open...riv/jazykVysledku
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  • cardiac hypertrophy; fibrosis; ventricular remodeling (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [B55EE5F3E00B]
http://linked.open...i/riv/nazevZdroje
  • Journal of Hypertension
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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  • 27
http://linked.open...iv/tvurceVysledku
  • Pelouch, Václav
  • Pecháňová, Olga
  • Paulis, L.
  • Adamcová, M.
  • Müllerová, M.
  • Šimko, F.
  • Bednárová, K.
  • Krajčírovičová, K.
http://linked.open...ain/vavai/riv/wos
  • 269549400002
http://linked.open...n/vavai/riv/zamer
issn
  • 0263-6352
number of pages
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