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  • The effects of indapamide, a thiazide-like diuretic, and captopril, an angiotensin-converting enzyme inhibitor, on spontaneous hypertension and the development of left ventricular hypertrophy (LVH), nitric oxide generation and oxidant status were investigated. Whereas captopril reduced LVH, indapamide enhanced NOS activity and decreased oxidative damage in the case of the combined treatment. The complex protective effects of the combined indapamide plus captopril treatment on hypertension are exerted via its effects on blood pressure, heart hypertrophy and vasorelaxation
  • The effects of indapamide, a thiazide-like diuretic, and captopril, an angiotensin-converting enzyme inhibitor, on spontaneous hypertension and the development of left ventricular hypertrophy (LVH), nitric oxide generation and oxidant status were investigated. Whereas captopril reduced LVH, indapamide enhanced NOS activity and decreased oxidative damage in the case of the combined treatment. The complex protective effects of the combined indapamide plus captopril treatment on hypertension are exerted via its effects on blood pressure, heart hypertrophy and vasorelaxation (en)
Title
  • Comparison of the effects of indapamide and captopril on the development of spontaneous hypertension
  • Comparison of the effects of indapamide and captopril on the development of spontaneous hypertension (en)
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  • Comparison of the effects of indapamide and captopril on the development of spontaneous hypertension
  • Comparison of the effects of indapamide and captopril on the development of spontaneous hypertension (en)
skos:notation
  • RIV/67985823:_____/09:00330723!RIV10-AV0-67985823
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA305/09/0336), Z(AV0Z50110509)
http://linked.open...iv/cisloPeriodika
  • Suppl.6
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http://linked.open...aciTvurceVysledku
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  • 307794
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  • RIV/67985823:_____/09:00330723
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  • cardiac hypertrophy; nitric oxide; oxidant status (en)
http://linked.open.../riv/klicoveSlovo
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  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [6A88FF313328]
http://linked.open...i/riv/nazevZdroje
  • Journal of Hypertension
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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  • 27
http://linked.open...iv/tvurceVysledku
  • Pecháňová, Olga
  • Paulis, L.
  • Šimko, F.
  • Sládková, M.
  • Jendeková, L.
  • Vranková, S.
http://linked.open...ain/vavai/riv/wos
  • 269549400009
http://linked.open...n/vavai/riv/zamer
issn
  • 0263-6352
number of pages
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