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  • Reactive oxygen species (ROS) are important intracellular signaling molecules. During increased oxidative stress and associated oxidative damage ROS are mediators of vascular injury in hypertension. Oxidative stress causes vascular injury by reducing nitric oxide bioavailability, altering endothelial function and vascular contraction/dilation, promoting vascular smooth muscle cell proliferation and hypertrophy, and increasing extracellular matrix deposition and inflammation. The present review focuses on the regulatory role of ROS on cell growth and cell cycle progression
  • Reactive oxygen species (ROS) are important intracellular signaling molecules. During increased oxidative stress and associated oxidative damage ROS are mediators of vascular injury in hypertension. Oxidative stress causes vascular injury by reducing nitric oxide bioavailability, altering endothelial function and vascular contraction/dilation, promoting vascular smooth muscle cell proliferation and hypertrophy, and increasing extracellular matrix deposition and inflammation. The present review focuses on the regulatory role of ROS on cell growth and cell cycle progression (en)
Title
  • Reactive oxygen species, cell growth, cell cycle progression and vascular remodeling in hypertension
  • Reactive oxygen species, cell growth, cell cycle progression and vascular remodeling in hypertension (en)
skos:prefLabel
  • Reactive oxygen species, cell growth, cell cycle progression and vascular remodeling in hypertension
  • Reactive oxygen species, cell growth, cell cycle progression and vascular remodeling in hypertension (en)
skos:notation
  • RIV/67985823:_____/07:00331655!RIV10-MSM-67985823
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(1M0510), Z(AV0Z50110509)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
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  • 446492
http://linked.open...ai/riv/idVysledku
  • RIV/67985823:_____/07:00331655
http://linked.open...riv/jazykVysledku
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  • cyclins; oxidative stress; cell proliferation (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [2D43FE2B4431]
http://linked.open...i/riv/nazevZdroje
  • Future Cardiology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 3
http://linked.open...iv/tvurceVysledku
  • Xu, S.
  • Vokurková, Martina
  • Touyz, R. M.
http://linked.open...n/vavai/riv/zamer
issn
  • 1479-6678
number of pages
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