About: Functional and structural pattern of arterial responses in hereditary hypertriglyceridemic and spontaneously hypertensive rats in early stage of experimental hypertension     Goto   Sponge   NotDistinct   Permalink

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  • Endothelium-derived nitric oxide (NO) plays an important role in regulation of vascular tone in the prenatal and early postnatal period. The aim of this paper was to determine the reactivity and accompanying structural changes in thoracic aorta from 4-week-old spontaneously hypertensive rats (SHR) and rats with hereditary hypertriglyceridemia (hHTG) in comparison with age-matched normotensive controls. Our observations indicate that in early stage of experimental hypertension NO-dependent relaxation is preserved so that putative impairment of this function provides no significant pathogenic contribution to the onset of hypertension in these two experimental models
  • Endothelium-derived nitric oxide (NO) plays an important role in regulation of vascular tone in the prenatal and early postnatal period. The aim of this paper was to determine the reactivity and accompanying structural changes in thoracic aorta from 4-week-old spontaneously hypertensive rats (SHR) and rats with hereditary hypertriglyceridemia (hHTG) in comparison with age-matched normotensive controls. Our observations indicate that in early stage of experimental hypertension NO-dependent relaxation is preserved so that putative impairment of this function provides no significant pathogenic contribution to the onset of hypertension in these two experimental models (en)
  • Endoteliální oxid dusnatý (NO) hraje významnou úlohu v regulaci cévního tonu v prenatální i časně postnatální periodě. Cílem práce byl změřit reaktivitu a strukturální změny v aortě čtyřtýdenních SHR a HTG potkanů ve srovnání s normotezními kontrolami stejného věku. Naše nálezy ukazují, že v časném stádiu vývoje experimentální hypertenze je NO-dependentní vasodilatace zachována, takže případné poruchy této funkce nepřispívají k patogenezi hypertenze u těchto dvou modelů (cs)
Title
  • Functional and structural pattern of arterial responses in hereditary hypertriglyceridemic and spontaneously hypertensive rats in early stage of experimental hypertension
  • Funkční a strukturální změny artérií u hereditárně hypertriglyceridemických a spontánně hypertenzních potkanů v časné fázi rozvoje hypertenze (cs)
  • Functional and structural pattern of arterial responses in hereditary hypertriglyceridemic and spontaneously hypertensive rats in early stage of experimental hypertension (en)
skos:prefLabel
  • Functional and structural pattern of arterial responses in hereditary hypertriglyceridemic and spontaneously hypertensive rats in early stage of experimental hypertension
  • Funkční a strukturální změny artérií u hereditárně hypertriglyceridemických a spontánně hypertenzních potkanů v časné fázi rozvoje hypertenze (cs)
  • Functional and structural pattern of arterial responses in hereditary hypertriglyceridemic and spontaneously hypertensive rats in early stage of experimental hypertension (en)
skos:notation
  • RIV/67985823:_____/06:00050054!RIV07-AV0-67985823
http://linked.open.../vavai/riv/strany
  • S65;S71
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(1M0510), Z(AV0Z50110509)
http://linked.open...iv/cisloPeriodika
  • S1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 476458
http://linked.open...ai/riv/idVysledku
  • RIV/67985823:_____/06:00050054
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • relaxation; contraction; vessel geometry (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [A472416CE330]
http://linked.open...i/riv/nazevZdroje
  • Physiological Research
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 55
http://linked.open...iv/tvurceVysledku
  • Kuneš, Jaroslav
  • Kristek, F.
  • Török, J.
  • Cebová, M.
  • Koprdová, R.
http://linked.open...n/vavai/riv/zamer
issn
  • 0862-8408
number of pages
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