About: Oxidation of glycerol-3-phosphate in porcine and bovineadrenal cortex mitochondria

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Srovnávali jsme schopnost prasečích mitochondrií z kůry nadledvin oxidovat glycerol-3-fosfát (GP). Ve srovnání s hovězími mitochondriemi kůry nadledvin, prasečí mitochondrie oxidovaly GP přibližně 3 x aktivněji (18.9 vs 6.1 nmol O2/min/mg proteinu v přítomnosti ADP) a aktivita mitochondriální glycerol-3-fosfátdehydrogenázy byla asi 4 x vyšší (33.4 vs 8.2 nmol/min/mg proteinu). Citlivost k rotenonu deoxykortikosterolové stimulace u GP oxidace ukázala, že prasečí mitochondrie z kůry nadledvin jsou schopné oxidovat GP, a tak vyrobit NADPH z GP pravděpodobně přes reverzibilní transport s energeticky závislou NADH-NADPH transhydrogenací (cs) The capabilities of porcine adrenal cortex mitochondria to oxidize glycerol-3-phosphate (GP) were studied. In comparison with bovine adrenal cortex mitochondria, porcine mitochondria oxidized GP about three times more actively (18.9 vs 6.1 nmol O2/min/mg protein in the presence of ADP) and the activity of mitochondrial glycerol-3-phosphate dehydrogenase was about four times higher (33.4 vs 8.2 nmol/min/mg protein). Rotenone sensitivity of deoxycorticosterone stimulation of GP oxidation indicated that porcine adrenal cortex mitochondria are able to oxidize GP and thus to generate NADPH from GP, presumably via reverse electron transport followed by energy-dependent NADH-NADPH transhydrogenation The capabilities of porcine adrenal cortex mitochondria to oxidize glycerol-3-phosphate (GP) were studied. In comparison with bovine adrenal cortex mitochondria, porcine mitochondria oxidized GP about three times more actively (18.9 vs 6.1 nmol O2/min/mg protein in the presence of ADP) and the activity of mitochondrial glycerol-3-phosphate dehydrogenase was about four times higher (33.4 vs 8.2 nmol/min/mg protein). Rotenone sensitivity of deoxycorticosterone stimulation of GP oxidation indicated that porcine adrenal cortex mitochondria are able to oxidize GP and thus to generate NADPH from GP, presumably via reverse electron transport followed by energy-dependent NADH-NADPH transhydrogenation (en)
Title	Oxidation of glycerol-3-phosphate in porcine and bovineadrenal cortex mitochondria Oxidace glycerol-3-fosfátu v mitochondriích kůry nadledvin u prasete a krávy (cs) Oxidation of glycerol-3-phosphate in porcine and bovineadrenal cortex mitochondria (en)
skos:prefLabel	Oxidation of glycerol-3-phosphate in porcine and bovineadrenal cortex mitochondria Oxidace glycerol-3-fosfátu v mitochondriích kůry nadledvin u prasete a krávy (cs) Oxidation of glycerol-3-phosphate in porcine and bovineadrenal cortex mitochondria (en)
skos:notation	RIV/67985823:_____/04:00108572!RIV/2005/AV0/A20005/N
http://linked.open.../vavai/riv/strany	1075;1080
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA305/04/0500), Z(AV0Z5011922)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Rauchová, Hana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	578673
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/04:00108572
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	adrenal cortex mitochondria;glycerol-3-phosphate;succinate (en)
http://linked.open.../riv/klicoveSlovo	glycerol-3-phosphate adrenal cortex mitochondria succinate
http://linked.open...odStatuVydavatele	PL - Polská republika
http://linked.open...ontrolniKodProRIV	[9FABD2A0F28C]
http://linked.open...i/riv/nazevZdroje	Acta Biochimica Polonica
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Oxidative stress induced by acute and chonic hypoxia: metabolic changes and membrane alterations
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	51
http://linked.open...iv/tvurceVysledku	Rauchová, Hana Lenaz, G. Antosiewicz, J. Kaczor, J. J. Popinigis, J.
http://linked.open...n/vavai/riv/zamer	Investigation of normal and pathological physiology of animals - the clarification of the physiological mechanisms operating in humans in health and disease
issn	0001-527X
number of pages	6 (xsd:int)

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