About: The effect of a kainate GluR5 receptor antagonist on responses of spinothalamic tract neurons in a model of peripheral neuropathy in primates

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About: The effect of a kainate GluR5 receptor antagonist on responses of spinothalamic tract neurons in a model of peripheral neuropathy in primates Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Our results suggest that kainate receptors are involved in synaptic activation of STT cells in the normal state and may also play an important role in pathological pain states such as peripheral neuropathy in primates. Kainate receptor antagonists could thus be useful for the treatment of certain forms of allodynia and hyperalgesia Our results suggest that kainate receptors are involved in synaptic activation of STT cells in the normal state and may also play an important role in pathological pain states such as peripheral neuropathy in primates. Kainate receptor antagonists could thus be useful for the treatment of certain forms of allodynia and hyperalgesia (en) Naše výsledky naznačují, že kainatové receptory jsou zapojeny do synaptické aktivace STT neuronů za normálního stavu, a že mohou také hrát významnou úlohu ve stavech patologické bolesti, jako je bolest neuropatického původu u primátů. Antagonisté kainátových receptorů mohou být proto užitečné pro léčbu určitých forem allodynie a hyperalgesie (cs)
Title	The effect of a kainate GluR5 receptor antagonist on responses of spinothalamic tract neurons in a model of peripheral neuropathy in primates The effect of a kainate GluR5 receptor antagonist on responses of spinothalamic tract neurons in a model of peripheral neuropathy in primates (en) Účinek antagonistů kainatových GLUR5 receptorů na odpovědi neuronů spinothalamického traktu v modelu periferní neuropatie u primátů (cs)
skos:prefLabel	The effect of a kainate GluR5 receptor antagonist on responses of spinothalamic tract neurons in a model of peripheral neuropathy in primates The effect of a kainate GluR5 receptor antagonist on responses of spinothalamic tract neurons in a model of peripheral neuropathy in primates (en) Účinek antagonistů kainatových GLUR5 receptorů na odpovědi neuronů spinothalamického traktu v modelu periferní neuropatie u primátů (cs)
skos:notation	RIV/67985823:_____/04:00103110!RIV/2005/AV0/A20005/N
http://linked.open.../vavai/riv/strany	151;161
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(AV0Z5011922)
http://linked.open...iv/cisloPeriodika	1-2
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Paleček, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	561783
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/04:00103110
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	kainate receptor;peripheral neuropathy;primate (en)
http://linked.open.../riv/klicoveSlovo	peripheral neuropathy primate kainate receptor
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[FA28FC44E354]
http://linked.open...i/riv/nazevZdroje	Pain
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	111
http://linked.open...iv/tvurceVysledku	Paleček, Jiří Iyengar, S. Willis, W. D. Carlton, S. M. Neugebauer, V.
http://linked.open...n/vavai/riv/zamer	Investigation of normal and pathological physiology of animals - the clarification of the physiological mechanisms operating in humans in health and disease
issn	0304-3959
number of pages	11 (xsd:int)

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