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  • We examinated cardioprotective effect of chronic hypoxia and time course of its recovery under normoxic conditions. The duration of cardioprotection induced by chronic hypoxia differs markedly, depending on the end point of ischemia/reperfusion injury examined. The residual protection on infarct size persisted for at least 35 day of normoxic recovery in contrast to the antiarrhythmic protection which disapppeared already during the first week of normoxic recovery.
  • We examinated cardioprotective effect of chronic hypoxia and time course of its recovery under normoxic conditions. The duration of cardioprotection induced by chronic hypoxia differs markedly, depending on the end point of ischemia/reperfusion injury examined. The residual protection on infarct size persisted for at least 35 day of normoxic recovery in contrast to the antiarrhythmic protection which disapppeared already during the first week of normoxic recovery. (en)
  • Studie se zabývala otázkou, jak dlouho přetrvává kardioprotektivní účinek chronické hypoxie po ukončení adaptace. Zjistili jsme, že citlivost chronicky hypoxického myokardu k ischemii po návratu do normoxie je odlišná v závislosti na studovaných projevech ischemie. Reziduální kardioprotektivní účinek na velikost infarktu přetrvával ještě po 35 dnech od ukončení adaptace na rozdíl od antiarytmického účinku, který vymizel již v průběhu prvního týdne v normoxii (cs)
Title
  • Myocardial infarct size-limiting effect of chronic hypoxia persists for five weeks of normoxic recovery
  • Myocardial infarct size-limiting effect of chronic hypoxia persists for five weeks of normoxic recovery (en)
  • Kardioprotektivní účinek adaptace na chronickou hypoxii snižující velikost infarktu přetrvává alespoň 5 týdnů (cs)
skos:prefLabel
  • Myocardial infarct size-limiting effect of chronic hypoxia persists for five weeks of normoxic recovery
  • Myocardial infarct size-limiting effect of chronic hypoxia persists for five weeks of normoxic recovery (en)
  • Kardioprotektivní účinek adaptace na chronickou hypoxii snižující velikost infarktu přetrvává alespoň 5 týdnů (cs)
skos:notation
  • RIV/67985823:_____/04:00103094!RIV/2005/AV0/A20005/N
http://linked.open.../vavai/riv/strany
  • 621;628
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA305/04/0465), P(LN00A069), Z(AV0Z5011922)
http://linked.open...iv/cisloPeriodika
  • 6
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 575140
http://linked.open...ai/riv/idVysledku
  • RIV/67985823:_____/04:00103094
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • chronic hypoxia;normoxic recovery;cardioprotection (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [BB649B67BF91]
http://linked.open...i/riv/nazevZdroje
  • Physiological Research
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 53
http://linked.open...iv/tvurceVysledku
  • Neckář, Jan
  • Kolář, František
  • Ošťádal, Bohuslav
http://linked.open...n/vavai/riv/zamer
issn
  • 0862-8408
number of pages
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