About: Intracellular spermine decreases open probability of N-methyl-d-aspartate receptor channels

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About: Intracellular spermine decreases open probability of N-methyl-d-aspartate receptor channels Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Spermin a další polyaminy jsou endogenními modulátory několika typů ionotropních receptorů včetně glutamátových receptorů. Předpokládáme, že inhibiční účinek intracelulárního sperminu na NMDA receptorech je odlišný od Ca2+-indukované inaktivace NMDA receptorů a sperminem indukované napěťově závislé inhibice AMPA/kainátových receptorů (cs) Spermine and related polyamines have been shown to be endogenous regulators of several ion channel types including ionotropic glutamate receptros. We propose that intracellular spermine has a direct inhibitory effect on NMDA receptors that is different from calcium-induced NMDA receptor inactivation and spernime-induced voltage-dependent inhibition of AMPA/kainate receptors Spermine and related polyamines have been shown to be endogenous regulators of several ion channel types including ionotropic glutamate receptros. We propose that intracellular spermine has a direct inhibitory effect on NMDA receptors that is different from calcium-induced NMDA receptor inactivation and spernime-induced voltage-dependent inhibition of AMPA/kainate receptors (en)
Title	Intracellular spermine decreases open probability of N-methyl-d-aspartate receptor channels Intracelulární spermin snižuje pravděpodobnost otevření NMDA receptorů (cs) Intracellular spermine decreases open probability of N-methyl-d-aspartate receptor channels (en)
skos:prefLabel	Intracellular spermine decreases open probability of N-methyl-d-aspartate receptor channels Intracelulární spermin snižuje pravděpodobnost otevření NMDA receptorů (cs) Intracellular spermine decreases open probability of N-methyl-d-aspartate receptor channels (en)
skos:notation	RIV/67985823:_____/04:00102565!RIV/2005/AV0/A20005/N
http://linked.open.../vavai/riv/strany	879;887
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA309/04/1537), P(LN00B122), Z(AV0Z5011922)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Vyklický ml., Ladislav Vlachová, Viktorie Vlček, Kamil Tureček, Rostislav Horák, Martin Petrovič, Miloš
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	568782
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/04:00102565
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	calcium;glatamate receptor;inactivation (en)
http://linked.open.../riv/klicoveSlovo	glatamate receptor calcium inactivation
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[B9B3F1A08FE4]
http://linked.open...i/riv/nazevZdroje	Neuroscience
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Study of the effects of neurosteroids on ionotropic glutamate receptors and synaptic transmission Neuropsychiatric Research Center
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	125
http://linked.open...iv/tvurceVysledku	Horák, Martin Vlachová, Viktorie Vyklický ml., Ladislav Vlček, Kamil Tureček, Rostislav Petrovič, Miloš
http://linked.open...n/vavai/riv/zamer	Investigation of normal and pathological physiology of animals - the clarification of the physiological mechanisms operating in humans in health and disease
issn	0306-4522
number of pages	9 (xsd:int)

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