About: Altered balance of vasoactive systems in experimental hypertension: The role of relative NO deficiency

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Posuzovali jsme úlohu relativního nedostatku NO (v poměru k existující sympatické vazokonstrikci) u různých forem experimentální hypertenze (genetické, sůl-dependentní a NO-deficientní). Zvláštní pozornost jsme věnovali interakcím reaktivních kyslíkových radikálů s metabolismem NO, metabolismem Ca2+ a regulací krevního tlaku. Naše současná pozornost je zaměřena na abnormální regulaci hladin cytosolického Ca2+ v hladkém svalu a endotelu cév u zvířat s hypertenzí (cs) The role of relative NO deficiency (compared to existing sympathetic vasoconstriction) was considered in various genetic, salt-dependent and NO-deficient forms of experimental hypertension. A special attention was paid to the interactions of reactive oxygen species with NO metabolism, cell Ca2+ handling and blood pressure regulation. Our current investigations are focused to abnormal regulation of cytosolic Ca2+ levels in smooth muscle and endothelium of hypertensive animals The role of relative NO deficiency (compared to existing sympathetic vasoconstriction) was considered in various genetic, salt-dependent and NO-deficient forms of experimental hypertension. A special attention was paid to the interactions of reactive oxygen species with NO metabolism, cell Ca2+ handling and blood pressure regulation. Our current investigations are focused to abnormal regulation of cytosolic Ca2+ levels in smooth muscle and endothelium of hypertensive animals (en)
Title	Altered balance of vasoactive systems in experimental hypertension: The role of relative NO deficiency Změna rovnováhy vazoaktivních systémů v experimentální hypertenzi: úloha relativního nedostatku NO (cs) Altered balance of vasoactive systems in experimental hypertension: The role of relative NO deficiency (en)
skos:prefLabel	Altered balance of vasoactive systems in experimental hypertension: The role of relative NO deficiency Změna rovnováhy vazoaktivních systémů v experimentální hypertenzi: úloha relativního nedostatku NO (cs) Altered balance of vasoactive systems in experimental hypertension: The role of relative NO deficiency (en)
skos:notation	RIV/67985823:_____/04:00102551!RIV/2005/AV0/A20005/N
http://linked.open.../vavai/riv/strany	S23;S34
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA305/03/0769), P(GP305/02/P066), P(IAA7011805), P(LN00A069), Z(AV0Z5011922)
http://linked.open...iv/cisloPeriodika	Suppl.1
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Pecháňová, Olga Zicha, Josef Kuneš, Jaroslav Vokurková, Martina Kadlecová, Michaela Rauchová, Hana Loukotová, Jana Dobešová, Zdeňka Hojná, Silvie
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	553933
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/04:00102551
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	NO deficiency;reactive oxygen species;calcium influx (en)
http://linked.open.../riv/klicoveSlovo	calcium influx NO deficiency reactive oxygen species
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[90FDA314C5CD]
http://linked.open...i/riv/nazevZdroje	Physiological Research
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	9 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Center for experimental research of cardiovascular diseases The search for quantitative trait loci and candidate genes responsible for the pathogenesis of hypertension and metabolic syndrome Influence of oxidative stress on cell calcium handling in genetic hypertension Oxygen free radicals and nitric oxide in the pathogenesis of age-dependent experimental hypertension: the attenuation of vasodilator mechanisms ...
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	53
http://linked.open...iv/tvurceVysledku	Kuneš, Jaroslav Zicha, Josef Kadlecová, Michaela Rauchová, Hana Vokurková, Martina Loukotová, Jana Dobešová, Zdenka Hojná, Silvie Pecháňová, Olga
http://linked.open...n/vavai/riv/zamer	Investigation of normal and pathological physiology of animals - the clarification of the physiological mechanisms operating in humans in health and disease
issn	0862-8408
number of pages	12 (xsd:int)

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