About: Does Cd36 gene play a key role in disturbed glucose and fatty acid metabolism in Prague hypertensive hypertriglyceridemic rats?

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Studovali jsme polymorfismus genu Cd36 u Pražského hypertriglyceridemického potkana (HTG) pro srovnání tohoto kmenu se spontánně hypertenzními potkany (SHR). Navzdory tomu, že HTG a SHR mají podobné metabolické abnormality, mutace Cd36, charakteristická pro SHR, chyběla u HTG kmene. Není pochyb o tom, že důležitou úlohu v patogenezi metabolického syndromu HTG potkanů hrají jiné geny než je CD36 (cs) The polymorphism of Cd36 gene in Prague hypertriglyceridemic (HTG) rat was investigated in order to compare this strain with spontaneously hypertensive rats (SHR). In spite of the fact that HTG and SHR had similar metabolic abnormalities, Cd36 mutation characteristic for SHR was absent in HTG strain. It is evident that genes other than Cd36 play an important role in pathogenesis of metabolic syndrome of HTG rats The polymorphism of Cd36 gene in Prague hypertriglyceridemic (HTG) rat was investigated in order to compare this strain with spontaneously hypertensive rats (SHR). In spite of the fact that HTG and SHR had similar metabolic abnormalities, Cd36 mutation characteristic for SHR was absent in HTG strain. It is evident that genes other than Cd36 play an important role in pathogenesis of metabolic syndrome of HTG rats (en)
Title	Does Cd36 gene play a key role in disturbed glucose and fatty acid metabolism in Prague hypertensive hypertriglyceridemic rats? Does Cd36 gene play a key role in disturbed glucose and fatty acid metabolism in Prague hypertensive hypertriglyceridemic rats? (en) Hraje gen Cd36 klíčovou úlohu při poruchách metabolismu glukózy a mastných kyselin u Pražského hypertenzního hypertriglyceridemického potkana? (cs)
skos:prefLabel	Does Cd36 gene play a key role in disturbed glucose and fatty acid metabolism in Prague hypertensive hypertriglyceridemic rats? Does Cd36 gene play a key role in disturbed glucose and fatty acid metabolism in Prague hypertensive hypertriglyceridemic rats? (en) Hraje gen Cd36 klíčovou úlohu při poruchách metabolismu glukózy a mastných kyselin u Pražského hypertenzního hypertriglyceridemického potkana? (cs)
skos:notation	RIV/67985823:_____/04:00102531!RIV/2005/AV0/A20005/N
http://linked.open.../vavai/riv/strany	265;271
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA305/03/0769), P(LN00A069), Z(AV0Z5011922)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Čejka, Jakub Zicha, Josef Kuneš, Jaroslav Kadlecová, Michaela
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	561027
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/04:00102531
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	hypertension;insulin resistance;metabolic syndrome (en)
http://linked.open.../riv/klicoveSlovo	hypertension - ischaemic heart disease - cardiac failure - vitamin D insulin resistance metabolic syndrome
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[54E6439997B9]
http://linked.open...i/riv/nazevZdroje	Physiological Research
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Center for experimental research of cardiovascular diseases The search for quantitative trait loci and candidate genes responsible for the pathogenesis of hypertension and metabolic syndrome
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	53
http://linked.open...iv/tvurceVysledku	Kuneš, Jaroslav Zicha, Josef Kadlecová, Michaela Čejka, Jakub
http://linked.open...n/vavai/riv/zamer	Investigation of normal and pathological physiology of animals - the clarification of the physiological mechanisms operating in humans in health and disease
issn	0862-8408
number of pages	7 (xsd:int)

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