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  • Pharmacogenetic analysis was carried out in F2 hybrid population derived from Prague hypertensive hypertriglyceridemic and normotensive normolipidemic Lewis rats. Several quantitative trait loci for particular blood pressure components (dependent on renin-angiotensin system, sympathetic nervous system or nitric oxide) were disclosed. This pharmacogenetic approach should enable to determine the main causative blood pressure regulating systems in hypertension.
  • Pharmacogenetic analysis was carried out in F2 hybrid population derived from Prague hypertensive hypertriglyceridemic and normotensive normolipidemic Lewis rats. Several quantitative trait loci for particular blood pressure components (dependent on renin-angiotensin system, sympathetic nervous system or nitric oxide) were disclosed. This pharmacogenetic approach should enable to determine the main causative blood pressure regulating systems in hypertension. (en)
Title
  • Resolving the composite trait of hypertension into its pharmacogenetic determinants by acute pharmacological modulation of blood pressure regulatory systems.
  • Resolving the composite trait of hypertension into its pharmacogenetic determinants by acute pharmacological modulation of blood pressure regulatory systems. (en)
skos:prefLabel
  • Resolving the composite trait of hypertension into its pharmacogenetic determinants by acute pharmacological modulation of blood pressure regulatory systems.
  • Resolving the composite trait of hypertension into its pharmacogenetic determinants by acute pharmacological modulation of blood pressure regulatory systems. (en)
skos:notation
  • RIV/67985823:_____/03:20030010!RIV/2004/AV0/A20004/N
http://linked.open.../vavai/riv/strany
  • 51;60
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(IAA7011711), Z(AV0Z5011922)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...dnocenehoVysledku
  • 625425
http://linked.open...ai/riv/idVysledku
  • RIV/67985823:_____/03:20030010
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • genetic analysis; blood pressure; vasoactive system balance (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [17AB86B61B84]
http://linked.open...i/riv/nazevZdroje
  • Journal of Molecular Medicine-JMM
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...ocetUcastnikuAkce
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http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 81
http://linked.open...iv/tvurceVysledku
  • Kuneš, Jaroslav
  • Zicha, Josef
  • Dobešová, Zdeňka
  • Hamet, P.
  • Tremblay, J.
  • Jacob, H. J.
  • Pausová, Z.
  • Deng, A. Y.
  • Sun, Y. L.
  • Ueno, T.
http://linked.open...n/vavai/riv/zamer
issn
  • 0946-2716
number of pages
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