About: Early changes in extrafusal and intrafusal muscle fibers following heterochronous isotransplantation.     Goto   Sponge   NotDistinct   Permalink

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  • The ultrastructure of regenerating intrafusal and extrafusal fibres was studied 18 hours to 30 days after heterochronous isotransplantation, when bupivacaine-treated EDL or soleus muscles from early postnatal rats were intramuscularly grafted into EDL muscles of adult inbred recipients. Similarly as in other models of mammalian muscle regeneration, surviving satellite cells gave rise to presumptive myoblasts multiplying within the preserved basal lamina tubes at day 4 after grafting, myoblasts fused to form myotubes with central myonuclei by day 6 after grafting. Extrafusal myotubes differentiated into thin muscle fibres by day 8, which progressively increased in diameter and their nuclei became localized subsarcolemmally from day 13 onwards. The basal laminae of some intrafusal fibres already contained one or more nascent myotubes by day 4 after grafting. Regenerated intrafusal fibres lacked the typical nuclear accumulations and their number varied from 1 to 8 fibres per spindle; additional fibres fo
  • The ultrastructure of regenerating intrafusal and extrafusal fibres was studied 18 hours to 30 days after heterochronous isotransplantation, when bupivacaine-treated EDL or soleus muscles from early postnatal rats were intramuscularly grafted into EDL muscles of adult inbred recipients. Similarly as in other models of mammalian muscle regeneration, surviving satellite cells gave rise to presumptive myoblasts multiplying within the preserved basal lamina tubes at day 4 after grafting, myoblasts fused to form myotubes with central myonuclei by day 6 after grafting. Extrafusal myotubes differentiated into thin muscle fibres by day 8, which progressively increased in diameter and their nuclei became localized subsarcolemmally from day 13 onwards. The basal laminae of some intrafusal fibres already contained one or more nascent myotubes by day 4 after grafting. Regenerated intrafusal fibres lacked the typical nuclear accumulations and their number varied from 1 to 8 fibres per spindle; additional fibres fo (en)
Title
  • Early changes in extrafusal and intrafusal muscle fibers following heterochronous isotransplantation.
  • Early changes in extrafusal and intrafusal muscle fibers following heterochronous isotransplantation. (en)
skos:prefLabel
  • Early changes in extrafusal and intrafusal muscle fibers following heterochronous isotransplantation.
  • Early changes in extrafusal and intrafusal muscle fibers following heterochronous isotransplantation. (en)
skos:notation
  • RIV/67985823:_____/01:20010274!RIV/2003/AV0/A20003/N
http://linked.open.../vavai/riv/strany
  • 473;484
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA304/00/1653), Z(AV0Z5011922)
http://linked.open...iv/cisloPeriodika
  • 5
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 678443
http://linked.open...ai/riv/idVysledku
  • RIV/67985823:_____/01:20010274
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • muscle transplantation; - degeneration and regeneration of muscle fibers; - extrafusal and intrafusal fibers (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [1272B02C7850]
http://linked.open...i/riv/nazevZdroje
  • Acta Neuropathologica
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...ocetUcastnikuAkce
http://linked.open...nichUcastnikuAkce
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 102
http://linked.open...iv/tvurceVysledku
  • Soukup, Tomáš
  • Jirmanová, Isa
http://linked.open...n/vavai/riv/zamer
issn
  • 0001-6322
number of pages
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