About: Altered Na+-K+ pump activity and plasma lipids in salt-hypertensive Dahl rats: relationship to Atp1a1 gene.

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About: Altered Na+-K+ pump activity and plasma lipids in salt-hypertensive Dahl rats: relationship to Atp1a1 gene. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We studied Na+-K+ pump activity in erythrocytes of Dahl salt-sensitive (SS/Jr) rats in relation to plasma lipids and blood pressure and the linkage of polymorphic microsatellite marker D2Arb18 (located within intron 1 and exon 2 of Atp1a1 gene) with various phenotypes in 130 SS/Jr x SR/Jr F2 rats. Our results indicate that abnormal cholesterol metabolism but not the Atp1a1 gene locus might represent an important factor for both high blood pressure and altered Na+-K+ pump function in salt hypertensive Dahl rats. We studied Na+-K+ pump activity in erythrocytes of Dahl salt-sensitive (SS/Jr) rats in relation to plasma lipids and blood pressure and the linkage of polymorphic microsatellite marker D2Arb18 (located within intron 1 and exon 2 of Atp1a1 gene) with various phenotypes in 130 SS/Jr x SR/Jr F2 rats. Our results indicate that abnormal cholesterol metabolism but not the Atp1a1 gene locus might represent an important factor for both high blood pressure and altered Na+-K+ pump function in salt hypertensive Dahl rats. (en)
Title	Altered Na+-K+ pump activity and plasma lipids in salt-hypertensive Dahl rats: relationship to Atp1a1 gene. Altered Na+-K+ pump activity and plasma lipids in salt-hypertensive Dahl rats: relationship to Atp1a1 gene. (en)
skos:prefLabel	Altered Na+-K+ pump activity and plasma lipids in salt-hypertensive Dahl rats: relationship to Atp1a1 gene. Altered Na+-K+ pump activity and plasma lipids in salt-hypertensive Dahl rats: relationship to Atp1a1 gene. (en)
skos:notation	RIV/67985823:_____/01:20010237!RIV/2003/AV0/A20003/N
http://linked.open.../vavai/riv/strany	99;104
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA305/00/1638), Z(AV0Z5011922)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Zicha, Josef Kuneš, Jaroslav Vokurková, Martina Dobešová, Zdeňka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	672891
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/01:20010237
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	F2 hybrids; - erythrocyte ion transport; - erythrocyte sodium content (en)
http://linked.open.../riv/klicoveSlovo	F2 hybrids - erythrocyte ion transport - erythrocyte sodium content
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[DCACFB433C22]
http://linked.open...i/riv/nazevZdroje	Physiological Genomics
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Ion transport abnormalities in hypertension: the role of altered lipid metabolism
http://linked.open...UplatneniVysledku	2001
http://linked.open...v/svazekPeriodika	6
http://linked.open...iv/tvurceVysledku	Kuneš, Jaroslav Zicha, Josef Vokurková, Martina Dobešová, Zdeňka Carr, F. Dominiczak, A. F. McBride, M. Negrin, C. D.
http://linked.open...n/vavai/riv/zamer	Investigation of normal and pathological physiology of animals - the clarification of the physiological mechanisms operating in humans in health and disease
issn	1094-8341
number of pages	6 (xsd:int)

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