About: IRESite - a Tool for The Examination of Viral and Cellular Internal Ribosome Entry Sites

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About: IRESite - a Tool for The Examination of Viral and Cellular Internal Ribosome Entry Sites Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The IRESite presents curated experimental evidence of many eukaryotic viral and cellular internal ribosome entry site (IRES) regions. The IRESite stores > 600 records and gradually evolved into a robust tool providing (i) biologically meaningful information regarding the IRESs and their experimental background as well as (ii) thorough concluding remarks to stored database entries and regularly updated evaluation of the reported IRES function. A substantial portion of the IRESite data results purely from in-house bioinformatic analyses of currently available sequences, in silico attempts to repeat published cloning experiments, DNA sequencing and restriction endonuclease verification of received plasmid DNA. IRESite contains a newly implemented tool for displaying RNA secondary structures and for searching through the structures currently stored in the database. The supplementary material contains an updated list of reported IRESs. The IRESite presents curated experimental evidence of many eukaryotic viral and cellular internal ribosome entry site (IRES) regions. The IRESite stores > 600 records and gradually evolved into a robust tool providing (i) biologically meaningful information regarding the IRESs and their experimental background as well as (ii) thorough concluding remarks to stored database entries and regularly updated evaluation of the reported IRES function. A substantial portion of the IRESite data results purely from in-house bioinformatic analyses of currently available sequences, in silico attempts to repeat published cloning experiments, DNA sequencing and restriction endonuclease verification of received plasmid DNA. IRESite contains a newly implemented tool for displaying RNA secondary structures and for searching through the structures currently stored in the database. The supplementary material contains an updated list of reported IRESs. (en)
Title	IRESite - a Tool for The Examination of Viral and Cellular Internal Ribosome Entry Sites IRESite - a Tool for The Examination of Viral and Cellular Internal Ribosome Entry Sites (en)
skos:prefLabel	IRESite - a Tool for The Examination of Viral and Cellular Internal Ribosome Entry Sites IRESite - a Tool for The Examination of Viral and Cellular Internal Ribosome Entry Sites (en)
skos:notation	RIV/67985807:_____/10:00340720!RIV10-MSM-67985807
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M06014), P(GA301/07/0607), P(LC06066), Z(MSM0021620813), Z(MSM0021620858)
http://linked.open...iv/cisloPeriodika	DB Issue
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Pospíšek, Martin
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav informatiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	320423
http://linked.open...ai/riv/idVysledku	RIV/67985807:_____/10:00340720
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	IRESite; IRES; translation; virus; database (en)
http://linked.open.../riv/klicoveSlovo	database virus translation IRESite IRES
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[E5B99DA082F4]
http://linked.open...i/riv/nazevZdroje	Nucleic Acids Research
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Centre of Biomedical Informatics Center for Environmental Microbiology Fuctional diversity of hepatitis C virus quasispecies evaluated by high-throughput analysis of IRES elements activities - implications for the therapy
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	38
http://linked.open...iv/tvurceVysledku	Mašek, T. Pospíšek, Martin Mokrejš, M. Vopálenský, V. Delbos, P. Hlubuček, P.
http://linked.open...n/vavai/riv/zamer	The Molecular Basis of Childhood Malignancies and Therapeutic Applications Signaling and cellular response mechanisms
issn	0305-1048
number of pages	6 (xsd:int)

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