About: Exhaled Leukotrienes and Bronchial Responsiveness to Methacholine in Patients with Seasonal Allergic Rhinitis

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Aim of the study was to investigate the relationship between the postseasonal increase in the concentration of leukotriene (LT) B4 and LTE4 in exhaled breath condensate (EBC) and bronchial responsiveness to methacholine (BRM) in patients with seasonal allergic rhinitis (SAR). In 28 patients with SAR and 50 healthy study patients, the leukotrienes were measured during and after the pollen season by gas chromatography/mass spectrometry. Following seasonal and postseasonal median values were measured in patients with SAR in comparison with control patients: LTB4: 131 and 90 pg/mL vs 80 and 79 pg/mL, P < .001 and P = .03, respectively; LTE4: 122 and 86 pg/mL vs 76 and 74 pg/mL, P < .001and P = .02, respectively. Five months after the pollen season, the concentrations of LTB4 and LTE4 decreased with respect to their seasonal values (P < .001). The seasonal and postseasonal increases in LTB4 and LTE4 concentrations in EBC correlated significantly with the later increase in BRM. Aim of the study was to investigate the relationship between the postseasonal increase in the concentration of leukotriene (LT) B4 and LTE4 in exhaled breath condensate (EBC) and bronchial responsiveness to methacholine (BRM) in patients with seasonal allergic rhinitis (SAR). In 28 patients with SAR and 50 healthy study patients, the leukotrienes were measured during and after the pollen season by gas chromatography/mass spectrometry. Following seasonal and postseasonal median values were measured in patients with SAR in comparison with control patients: LTB4: 131 and 90 pg/mL vs 80 and 79 pg/mL, P < .001 and P = .03, respectively; LTE4: 122 and 86 pg/mL vs 76 and 74 pg/mL, P < .001and P = .02, respectively. Five months after the pollen season, the concentrations of LTB4 and LTE4 decreased with respect to their seasonal values (P < .001). The seasonal and postseasonal increases in LTB4 and LTE4 concentrations in EBC correlated significantly with the later increase in BRM. (en)
Title	Exhaled Leukotrienes and Bronchial Responsiveness to Methacholine in Patients with Seasonal Allergic Rhinitis Exhaled Leukotrienes and Bronchial Responsiveness to Methacholine in Patients with Seasonal Allergic Rhinitis (en)
skos:prefLabel	Exhaled Leukotrienes and Bronchial Responsiveness to Methacholine in Patients with Seasonal Allergic Rhinitis Exhaled Leukotrienes and Bronchial Responsiveness to Methacholine in Patients with Seasonal Allergic Rhinitis (en)
skos:notation	RIV/67985807:_____/09:00338859!RIV10-AV0-67985807
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(NL7024), Z(AV0Z10300504)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Horáček, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav informatiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	314125
http://linked.open...ai/riv/idVysledku	RIV/67985807:_____/09:00338859
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	allergic rhinitis; asthma; breath condensate; leukotrienes; gas chromatography; mass spectrometry analysis (en)
http://linked.open.../riv/klicoveSlovo	gas chromatography leukotrienes allergic rhinitis asthma breath condensate mass spectrometry analysis
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[E5848A2E03F2]
http://linked.open...i/riv/nazevZdroje	Annals of Allergy Asthma & Immunology
http://linked.open...in/vavai/riv/obor	FN
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Biomarkers of airways inflammation in the breath condensate of children with asthma as a new noninvasive method of the asthma monitoring.
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	102
http://linked.open...iv/tvurceVysledku	Malý, Marek Čáp, P. Pehal, F. Pelikán, Z.
http://linked.open...ain/vavai/riv/wos	000263084000004
http://linked.open...n/vavai/riv/zamer	Informatika pro informační společnost: modely, algoritmy, aplikace
issn	1081-1206
number of pages	7 (xsd:int)

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