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rdf:type
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Description
| - Effect of advanced glycation end products (AGEs) in the pathogenesis of cancer could be diminished by interaction with soluable RAGE or by reducing AGE-precusors via glyoxalase I. Glu111Ala polymorphism of glyoxalaseI gene, AGEs, and sRAGE serum levels were studied in 113 breast cancer patients and in 58 controls. Higher frequency of the mutated C allele was found in patients with negative estrogen receptors and in patients in clinical stage III compared to controls (P<0.05). The presence of the C allele could represent a negative prognostic factor; however, further studies are needed to confirm this hypothesis.
- Effect of advanced glycation end products (AGEs) in the pathogenesis of cancer could be diminished by interaction with soluable RAGE or by reducing AGE-precusors via glyoxalase I. Glu111Ala polymorphism of glyoxalaseI gene, AGEs, and sRAGE serum levels were studied in 113 breast cancer patients and in 58 controls. Higher frequency of the mutated C allele was found in patients with negative estrogen receptors and in patients in clinical stage III compared to controls (P<0.05). The presence of the C allele could represent a negative prognostic factor; however, further studies are needed to confirm this hypothesis. (en)
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Title
| - Glyoxalase I Glu111Ala Polymorphism in Patients with Breast Cancer
- Glyoxalase I Glu111Ala Polymorphism in Patients with Breast Cancer (en)
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skos:prefLabel
| - Glyoxalase I Glu111Ala Polymorphism in Patients with Breast Cancer
- Glyoxalase I Glu111Ala Polymorphism in Patients with Breast Cancer (en)
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skos:notation
| - RIV/67985807:_____/09:00332958!RIV10-AV0-67985807
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - Z(AV0Z10300504), Z(MZ0VFN2005)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/67985807:_____/09:00332958
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - glyoxalase I; advanced glycation end products; breast cancer (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Zvára, Karel
- Kalousová, M.
- Zima, T.
- Germanová, A.
- Jáchymová, M.
- Germanová, Al.
- Tesarová, P.
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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