About: Establishment of the 1st World Health International Genetic Reference Panel for quantitation of BCR-ABL mRNA.     Goto   Sponge   NotDistinct   Permalink

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  • Serial quantitation of BCR-ABL mRNA levels is an important indicator of therapeutic response for patients with chronic myelogenous leukemia and Philadelphia chromosome–positive acute lymphoblastic leukemia, but there is substantial variation in the real-time quantitative polymerase chain reaction methodologies used by different testing laboratories. To help improve the comparability of results between centers we sought to develop accredited reference reagents that are directly linked to the BCR-ABL international scale.
  • Serial quantitation of BCR-ABL mRNA levels is an important indicator of therapeutic response for patients with chronic myelogenous leukemia and Philadelphia chromosome–positive acute lymphoblastic leukemia, but there is substantial variation in the real-time quantitative polymerase chain reaction methodologies used by different testing laboratories. To help improve the comparability of results between centers we sought to develop accredited reference reagents that are directly linked to the BCR-ABL international scale. (en)
Title
  • Establishment of the 1st World Health International Genetic Reference Panel for quantitation of BCR-ABL mRNA.
  • Establishment of the 1st World Health International Genetic Reference Panel for quantitation of BCR-ABL mRNA. (en)
skos:prefLabel
  • Establishment of the 1st World Health International Genetic Reference Panel for quantitation of BCR-ABL mRNA.
  • Establishment of the 1st World Health International Genetic Reference Panel for quantitation of BCR-ABL mRNA. (en)
skos:notation
  • RIV/65269705:_____/10:#0001189!RIV11-MZ0-65269705
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  • RIV/65269705:_____/10:#0001189
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  • BCR-ABL (en)
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  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [57E2E80442A0]
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  • 116
http://linked.open...iv/tvurceVysledku
  • Dvořáková, Dana
  • White, Helen E
issn
  • 1528-0020
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