About: The effects of lidocaine on bupivacaine-induced cardiotoxicity in the isolated rat heart     Goto   Sponge   NotDistinct   Permalink

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  • Bupivacaine is a widely used long-acting local anesthetic. In clinical practice, a mixture of bupivacaine and lidocaine is often used in order to combine the faster onset of sensory blockade of lidocaine with more profound and longer duration of blockade by bupivacaine. The aim of this study was to compare the cardiotoxicity of large doses of bupivacaine with lidocaine in the isolated rat heart and to estimate whether or not the addition of lidocaine in clinically relevant concentration increases bupivacaine-induced toxicity.
  • Bupivacaine is a widely used long-acting local anesthetic. In clinical practice, a mixture of bupivacaine and lidocaine is often used in order to combine the faster onset of sensory blockade of lidocaine with more profound and longer duration of blockade by bupivacaine. The aim of this study was to compare the cardiotoxicity of large doses of bupivacaine with lidocaine in the isolated rat heart and to estimate whether or not the addition of lidocaine in clinically relevant concentration increases bupivacaine-induced toxicity. (en)
Title
  • The effects of lidocaine on bupivacaine-induced cardiotoxicity in the isolated rat heart
  • The effects of lidocaine on bupivacaine-induced cardiotoxicity in the isolated rat heart (en)
skos:prefLabel
  • The effects of lidocaine on bupivacaine-induced cardiotoxicity in the isolated rat heart
  • The effects of lidocaine on bupivacaine-induced cardiotoxicity in the isolated rat heart (en)
skos:notation
  • RIV/65269705:_____/10:#0001080!RIV11-GA0-65269705
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA102/07/1473), V, Z(MSM0021622402)
http://linked.open...iv/cisloPeriodika
  • Suppl. 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 256325
http://linked.open...ai/riv/idVysledku
  • RIV/65269705:_____/10:#0001080
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • bupivacaine (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [25EE5E1C777B]
http://linked.open...i/riv/nazevZdroje
  • Physiological Reasearch
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 59
http://linked.open...iv/tvurceVysledku
  • Křikava, Ivo
  • Ševčík, Pavel
  • Štourač, Petr
http://linked.open...ain/vavai/riv/wos
  • 000279049100010
http://linked.open...n/vavai/riv/zamer
issn
  • 0862-8408
number of pages
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