About: Evaluation of HGF and Endostati in the Bone Marrow of Patients wtih Multiple Myeloma and the Effect of Peripheral Blood Admixture

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Evaluation of HGF and Endostati in the Bone Marrow of Patients wtih Multiple Myeloma and the Effect of Peripheral Blood Admixture Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The aim of our study was to evaluate the concentration changes in the proangiogenic hepatocyte growth factor (HGF) and antiangiogenic endostatin during the sampling of large bone marrow volumes in patients with multiple myeloma. HGF and endostatin concentrations were measured in the 1st ml, the 5th ml, the 19th ml, the 30th ml, and the 45th ml of the sample. Concentrations of HGF, which is produced by bone marrow and myeloma cells, decreased significantly in the course of BM sampling due to the admixture of peripheral blood. Endostatin concentrations did not change significantly during the procedure of sampling, as endostatin is mainly secreted by the parenchymatous organs such as liver, lungs, and others. In conclusion, the admixture of the peripheral blood could be partly responsible for conflicting results of studies of HGF in multiple myeloma. Standardisation of HGF sampling is required for valid comparisons between different studies. The aim of our study was to evaluate the concentration changes in the proangiogenic hepatocyte growth factor (HGF) and antiangiogenic endostatin during the sampling of large bone marrow volumes in patients with multiple myeloma. HGF and endostatin concentrations were measured in the 1st ml, the 5th ml, the 19th ml, the 30th ml, and the 45th ml of the sample. Concentrations of HGF, which is produced by bone marrow and myeloma cells, decreased significantly in the course of BM sampling due to the admixture of peripheral blood. Endostatin concentrations did not change significantly during the procedure of sampling, as endostatin is mainly secreted by the parenchymatous organs such as liver, lungs, and others. In conclusion, the admixture of the peripheral blood could be partly responsible for conflicting results of studies of HGF in multiple myeloma. Standardisation of HGF sampling is required for valid comparisons between different studies. (en)
Title	Evaluation of HGF and Endostati in the Bone Marrow of Patients wtih Multiple Myeloma and the Effect of Peripheral Blood Admixture Evaluation of HGF and Endostati in the Bone Marrow of Patients wtih Multiple Myeloma and the Effect of Peripheral Blood Admixture (en)
skos:prefLabel	Evaluation of HGF and Endostati in the Bone Marrow of Patients wtih Multiple Myeloma and the Effect of Peripheral Blood Admixture Evaluation of HGF and Endostati in the Bone Marrow of Patients wtih Multiple Myeloma and the Effect of Peripheral Blood Admixture (en)
skos:notation	RIV/65269705:_____/09:#0000797!RIV10-MZ0-65269705
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(LC06027), P(NR9225)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Pour, Luděk Penka, Miroslav Vorlíček, Jiří Říhová, Lucie Hájek, Roman Adam, Zdeněk
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Brno / (nerozlišená součást)
http://linked.open...dnocenehoVysledku	313860
http://linked.open...ai/riv/idVysledku	RIV/65269705:_____/09:#0000797
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Multiple myeloma (en)
http://linked.open.../riv/klicoveSlovo	Multiple myeloma
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[EEA7D424EBA0]
http://linked.open...i/riv/nazevZdroje	Scripta medica
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	University Research Centre - Czech Myeloma Group Optimalization of the therapy of myeloma patients in Czech republic
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	82
http://linked.open...iv/tvurceVysledku	Adam, Zdeněk Hájek, Roman Penka, Miroslav Vorlíček, Jiří Pour, L. Kovářová, Lucie
issn	1211-3395
number of pages	4 (xsd:int)

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 48 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software