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| rdf:type
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| Description
| - Anelloviridae family contains small DNA viruses with circular, single-stranded genomes. Torque teno viruses (TTV) with a genome of 3,8 - 3,9 kb show an extensive genetic variability. The numerous TTV species and genotypes described so far have been classified into five phylogenetic groups with complete nucleotide sequence divergence of } 50%. Frequent and early acquisition of multiple anellovirus infection during infancy in humans has been reported. TTV is a ubiquitous virus, infecting chronically }80% of the human population throughout the world; however, the pathogenic potential remains unclear. TTV has been detected in serum, saliva, breast milk, tears, semen and cervical smears, and has been shown to be secreted via bile into feces. Despite high genetic divergence, all of the TTV isolates show a conserved genetic organization with a coding region containing the major open reading frame, ORF1, an overlapping ORF2 and several shorter ORFs. Common and most conserved is an untranslated region containing a GC-rich part. The characterization of shorter viral genomes with similar genomic organization of length about 3200 kb (Torque teno midi virus, TTMDV) and 2800 kb (Torque teno mini virus, TTMV) revealed that the heterogeneity of these newly discovered viruses is not restricted to sequence diversity but is also extended to genome length. TTV infection is not restricted to humans; various animal species including non-human primates, tupaias, livestock and some companion animals carry a wide range of highly divergent TTV-like viruses. From non-human primates, the full length genomes of TTV, TTMV and TTMDV are so far known only from chimpanzees. Here we describe the almost full length genomes (except the GC rich region) and their phylogenetic analysis of two TTMVs isolated from serum of one captive living gorilla. These are the first full length genomes of anelloviruses originated from wild born, captive living male of Gorilla gorilla species.
- Anelloviridae family contains small DNA viruses with circular, single-stranded genomes. Torque teno viruses (TTV) with a genome of 3,8 - 3,9 kb show an extensive genetic variability. The numerous TTV species and genotypes described so far have been classified into five phylogenetic groups with complete nucleotide sequence divergence of } 50%. Frequent and early acquisition of multiple anellovirus infection during infancy in humans has been reported. TTV is a ubiquitous virus, infecting chronically }80% of the human population throughout the world; however, the pathogenic potential remains unclear. TTV has been detected in serum, saliva, breast milk, tears, semen and cervical smears, and has been shown to be secreted via bile into feces. Despite high genetic divergence, all of the TTV isolates show a conserved genetic organization with a coding region containing the major open reading frame, ORF1, an overlapping ORF2 and several shorter ORFs. Common and most conserved is an untranslated region containing a GC-rich part. The characterization of shorter viral genomes with similar genomic organization of length about 3200 kb (Torque teno midi virus, TTMDV) and 2800 kb (Torque teno mini virus, TTMV) revealed that the heterogeneity of these newly discovered viruses is not restricted to sequence diversity but is also extended to genome length. TTV infection is not restricted to humans; various animal species including non-human primates, tupaias, livestock and some companion animals carry a wide range of highly divergent TTV-like viruses. From non-human primates, the full length genomes of TTV, TTMV and TTMDV are so far known only from chimpanzees. Here we describe the almost full length genomes (except the GC rich region) and their phylogenetic analysis of two TTMVs isolated from serum of one captive living gorilla. These are the first full length genomes of anelloviruses originated from wild born, captive living male of Gorilla gorilla species. (en)
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| Title
| - TTMV co-infection in wild born captive living gorilla
- TTMV co-infection in wild born captive living gorilla (en)
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| skos:prefLabel
| - TTMV co-infection in wild born captive living gorilla
- TTMV co-infection in wild born captive living gorilla (en)
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| skos:notation
| - RIV/62157124:16810/13:43872482!RIV14-MSM-16810___
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/62157124:16810/13:43872482
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - gorilla; living; captive; born; wild; co-infection; TTMV (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...vavai/riv/projekt
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| http://linked.open...UplatneniVysledku
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| http://linked.open...iv/tvurceVysledku
| - Celer, Vladimír
- Hrazdilová, Kristýna
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| http://localhost/t...ganizacniJednotka
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