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Description
  • Eudragit(R)NM, was investigated as the matrix former in combination with microcrystalline cellulose as an insoluble filler for preparing controlled-release tablets containing model drugs with different solubility. A desirable release profile (at pH 6.8) was achieved only for freely soluble drugs when the ratio of drug/insoluble filler was 1:1 and polymer concentration ranged in interval 11.3-13.8% in tablets. Presented composition of matrix systems was not suitable for the incorporation of poorly soluble drugs
  • Eudragit(R)NM, was investigated as the matrix former in combination with microcrystalline cellulose as an insoluble filler for preparing controlled-release tablets containing model drugs with different solubility. A desirable release profile (at pH 6.8) was achieved only for freely soluble drugs when the ratio of drug/insoluble filler was 1:1 and polymer concentration ranged in interval 11.3-13.8% in tablets. Presented composition of matrix systems was not suitable for the incorporation of poorly soluble drugs (en)
Title
  • The Development of Eudragit(R) NM-Based Controlled Release Matrix Tablets
  • The Development of Eudragit(R) NM-Based Controlled Release Matrix Tablets (en)
skos:prefLabel
  • The Development of Eudragit(R) NM-Based Controlled Release Matrix Tablets
  • The Development of Eudragit(R) NM-Based Controlled Release Matrix Tablets (en)
skos:notation
  • RIV/62157124:16370/12:43871088!RIV13-MSM-16370___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • S
http://linked.open...iv/cisloPeriodika
  • 4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...dnocenehoVysledku
  • 130787
http://linked.open...ai/riv/idVysledku
  • RIV/62157124:16370/12:43871088
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  • matrix tablets, Eudragit(R) NM, drug solubility, microcrystalline cellulose, dissolution profile (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • LT - Litevská republika
http://linked.open...ontrolniKodProRIV
  • [D7A8A6A91858]
http://linked.open...i/riv/nazevZdroje
  • Medicina-Lithuania
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 48
http://linked.open...iv/tvurceVysledku
  • Bajerová, Martina
  • Bernatoniene, Jurga
  • Dvořáčková, Kateřina
  • Gajdziok, Jan
  • Muselík, Jan
  • Rabišková, Miloslava
  • Kaledaite, Rasa
  • Peči?ra, Rimantas
  • Lažauskas, Robertas
http://linked.open...ain/vavai/riv/wos
  • 000309628200004
issn
  • 1010-660X
number of pages
http://localhost/t...ganizacniJednotka
  • 16370
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