About: Evaluation of the Antiradical Activity of Schisandra Chinensis Lignans Using Different Experimental Models

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The in vitro antiradical activity of Schisandra chinensis lignans was investigated using DPPH, ABTS(+), Fenton reaction inhibition and tyrosine-nitration inhibition assays, as were the in vivo antidiabetic activities of selected lignans in an animal model of alloxan-induced diabetes. Different degrees of antiradical activity were found, depending upon the structural parameters of the tested compounds. Unfortunately, the compounds showed no antidiabetic activity in concentration range tested. The in vitro antiradical activity of Schisandra chinensis lignans was investigated using DPPH, ABTS(+), Fenton reaction inhibition and tyrosine-nitration inhibition assays, as were the in vivo antidiabetic activities of selected lignans in an animal model of alloxan-induced diabetes. Different degrees of antiradical activity were found, depending upon the structural parameters of the tested compounds. Unfortunately, the compounds showed no antidiabetic activity in concentration range tested. (en)
Title	Evaluation of the Antiradical Activity of Schisandra Chinensis Lignans Using Different Experimental Models Evaluation of the Antiradical Activity of Schisandra Chinensis Lignans Using Different Experimental Models (en)
skos:prefLabel	Evaluation of the Antiradical Activity of Schisandra Chinensis Lignans Using Different Experimental Models Evaluation of the Antiradical Activity of Schisandra Chinensis Lignans Using Different Experimental Models (en)
skos:notation	RIV/62157124:16370/10:00002608!RIV11-GA0-16370___
http://linked.open...avai/riv/aktivita	P S
http://linked.open...avai/riv/aktivity	P(1A8666), P(GA522/07/0995), S
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Šmejkal, Karel Kramářová, Eva Dvorská, Margita Žemlička, Milan Kubínová, Renáta Suchý, Pavel Muselík, Jan Vančo, Ján
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Veterinární a farmaceutická univerzita Brno / Farmaceutická fakulta
http://linked.open...dnocenehoVysledku	257905
http://linked.open...ai/riv/idVysledku	RIV/62157124:16370/10:00002608
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Schisandra chinensis; dibenzocyclooctadiene lignans; antiradical; diabetes mellitus (en)
http://linked.open.../riv/klicoveSlovo	Schisandra chinensis antiradical diabetes mellitus - insulin resistance - ethiopathogenesis - diagnostic criteria - late complications - advanced age - treatment dibenzocyclooctadiene lignans
http://linked.open...odStatuVydavatele	CH - Švýcarská konfederace
http://linked.open...ontrolniKodProRIV	[842C6F706BF4]
http://linked.open...i/riv/nazevZdroje	Molecules
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	8 (xsd:int)
http://linked.open...cetTvurcuVysledku	14 (xsd:int)
http://linked.open...vavai/riv/projekt	Verification of antidiabetic effect of ethnobotanicaly important herbal medicines Regulation of secondary metabolites biosynthesis in cell culture of Schisandra chinensis
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	15
http://linked.open...iv/tvurceVysledku	Kubínová, Renáta Muselík, Jan Suchý, Pavel Šmejkal, Karel Žemlička, Milan Dall'Acqua, Stefano Vančo, Ján Slanina, Jiří Innocenti, Gabbriella Šlapetová, Tereza Kramářová, Eva Dvorská, Margita Krmenčík, Pavel Kalvarová, Karolína
http://linked.open...ain/vavai/riv/wos	000275956900011
issn	1420-3049
number of pages	9 (xsd:int)
http://localhost/t...ganizacniJednotka	16370

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