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Description
| - In the present paper we describe results on the synthesis and lipophilicity determination of a series of biologically active compounds based on their heterocyclic structure. For synthesis of styrylquinoline-based compounds we applied microwave irradiation and solid phase techniques. The correlation between RP-HPLC retention parameter log k (the logarithm of retention factor k) and log P data calculated in various ways is discussed, as well as, the relationships between the lipophilicity and the chemical structure of the studied compounds.
- In the present paper we describe results on the synthesis and lipophilicity determination of a series of biologically active compounds based on their heterocyclic structure. For synthesis of styrylquinoline-based compounds we applied microwave irradiation and solid phase techniques. The correlation between RP-HPLC retention parameter log k (the logarithm of retention factor k) and log P data calculated in various ways is discussed, as well as, the relationships between the lipophilicity and the chemical structure of the studied compounds. (en)
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Title
| - RP-HPLC Determination of Drug Lipophilicity in Series of Quinoline Derivatives
- RP-HPLC Determination of Drug Lipophilicity in Series of Quinoline Derivatives (en)
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skos:prefLabel
| - RP-HPLC Determination of Drug Lipophilicity in Series of Quinoline Derivatives
- RP-HPLC Determination of Drug Lipophilicity in Series of Quinoline Derivatives (en)
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skos:notation
| - RIV/62157124:16370/09:00002075!RIV10-MSM-16370___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/62157124:16370/09:00002075
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Lipophilicity; RP-HPLC; Microwave synthesis; Quinoline derivatives (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Central European Journal of Chemistry
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Dohnal, Jiří
- Jampílek, Josef
- Polański, Jarosław
- Musioł, Robert
- Finster, Jacek
- Podeszwa, Barbara
- Tabak, Dominik
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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