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Description
  • Byly stanoveny pKa hodnoty. (cs)
  • Accurate determination of pK(a) values is important for proper characterization of newly synthesized molecules. In this work we have used CZE for determination of pKa values of new compounds prepared from intermediates, 2, 3 and 4-(2-chloro-acetylamino)phenoxyacetic acids, by substituting chloride for 2-oxo-pyrrolidine, 2-oxo-piperidine or 2-oxo-azepane. These substances are expected to have a cognition enhancing activity and free radicals scavenging effect.
  • Accurate determination of pK(a) values is important for proper characterization of newly synthesized molecules. In this work we have used CZE for determination of pKa values of new compounds prepared from intermediates, 2, 3 and 4-(2-chloro-acetylamino)phenoxyacetic acids, by substituting chloride for 2-oxo-pyrrolidine, 2-oxo-piperidine or 2-oxo-azepane. These substances are expected to have a cognition enhancing activity and free radicals scavenging effect. (en)
Title
  • Determination of dissociation constants of compounds with potential cognition enhncing activity by capillary zone electrophoresis
  • Determination of dissociation constants of compounds with potential cognition enhncing activity by capillary zone electrophoresis (en)
  • Stanovení disociačních konstant potenciálních posilovačů kognitivních funkcí metodou kapilární zonové elektroforézy (cs)
skos:prefLabel
  • Determination of dissociation constants of compounds with potential cognition enhncing activity by capillary zone electrophoresis
  • Determination of dissociation constants of compounds with potential cognition enhncing activity by capillary zone electrophoresis (en)
  • Stanovení disociačních konstant potenciálních posilovačů kognitivních funkcí metodou kapilární zonové elektroforézy (cs)
skos:notation
  • RIV/62157124:16370/05:00000019!RIV06-MSM-16370___
http://linked.open.../vavai/riv/strany
  • 4429-4439
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM 163700003)
http://linked.open...iv/cisloPeriodika
  • 23
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 517580
http://linked.open...ai/riv/idVysledku
  • RIV/62157124:16370/05:00000019
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • capillary zone electrophoresis; dissociation constant; potential nootropics; spectrophotometry (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [EB9CEBEC5862]
http://linked.open...i/riv/nazevZdroje
  • Electrophoresis
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 26
http://linked.open...iv/tvurceVysledku
  • Křivánková, Ludmila
  • Lišková, Anna
http://linked.open...n/vavai/riv/zamer
issn
  • 0173-0835
number of pages
http://localhost/t...ganizacniJednotka
  • 16370
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