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  • Previous studies demonstrated the toxic effects of cyanobacteria in Japanese quails (Coturnix coturnix japonica) in various experimental set-ups including acute, sub-chronic and reproduction toxicity, coexposures with toxic metals and the Newcastle vaccination. This study aimed to assess the testicular toxicity of a complex cyanobacterial biomass administered to Japanese quails in the feed for eight weeks (daily dose of 61.62 mg microcystins pro toto including 26.54 mg MC-RR, 7.62 mg MC-YR and 27.39 mg MC-LR). There was no mortality in the controls or the biomass-exposed birds. However, males exposed to cyanobacteria in the feed showed moderate to marked atrophy of the seminiferous tubular epithelium with only sparse numbers of the developmental stages of spermatozoa and Sertoli cells. Biomassexposed birds had elevated catalase activities but decreased glutathione peroxidase activities and surprisingly lower levels of lipid peroxides in the testes. The other biochemical parameters studied (i.e., glutathione level and glutathione reductase, glutathione-S-transferase and superoxide dismutase activities) showed no differences. The cell defensive system protecting testicular tissue from the damage associated with toxic effects of the complex cyanobacterial biomass seemed to be insufficient and partly depleted after the chronic exposure of male birds to this biomass.
  • Previous studies demonstrated the toxic effects of cyanobacteria in Japanese quails (Coturnix coturnix japonica) in various experimental set-ups including acute, sub-chronic and reproduction toxicity, coexposures with toxic metals and the Newcastle vaccination. This study aimed to assess the testicular toxicity of a complex cyanobacterial biomass administered to Japanese quails in the feed for eight weeks (daily dose of 61.62 mg microcystins pro toto including 26.54 mg MC-RR, 7.62 mg MC-YR and 27.39 mg MC-LR). There was no mortality in the controls or the biomass-exposed birds. However, males exposed to cyanobacteria in the feed showed moderate to marked atrophy of the seminiferous tubular epithelium with only sparse numbers of the developmental stages of spermatozoa and Sertoli cells. Biomassexposed birds had elevated catalase activities but decreased glutathione peroxidase activities and surprisingly lower levels of lipid peroxides in the testes. The other biochemical parameters studied (i.e., glutathione level and glutathione reductase, glutathione-S-transferase and superoxide dismutase activities) showed no differences. The cell defensive system protecting testicular tissue from the damage associated with toxic effects of the complex cyanobacterial biomass seemed to be insufficient and partly depleted after the chronic exposure of male birds to this biomass. (en)
Title
  • Testicular toxicity of cyanobacterial biomass in Japanese quails
  • Testicular toxicity of cyanobacterial biomass in Japanese quails (en)
skos:prefLabel
  • Testicular toxicity of cyanobacterial biomass in Japanese quails
  • Testicular toxicity of cyanobacterial biomass in Japanese quails (en)
skos:notation
  • RIV/62157124:16270/11:43870284!RIV15-MSM-16270___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(ED0001/01/01), S, Z(MSM0021622412), Z(MSM6215712402)
http://linked.open...iv/cisloPeriodika
  • 6
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 234890
http://linked.open...ai/riv/idVysledku
  • RIV/62157124:16270/11:43870284
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Oxidative stress; Testicular atrophy; Histopathology; Sub-lethal exposure; Microcystins; Birds (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • BE - Belgické království
http://linked.open...ontrolniKodProRIV
  • [C1A4DB469EDE]
http://linked.open...i/riv/nazevZdroje
  • Harmful Algae
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 10
http://linked.open...iv/tvurceVysledku
  • Banďouchová, Hana
  • Damková, Veronika
  • Hilscherová, Klára
  • Novotný, Ladislav
  • Pecková, Lucie
  • Pikula, Jiří
  • Pohanka, Miroslav
  • Sedláčková, Jana
  • Vitula, František
  • Paskova, Veronika
http://linked.open...ain/vavai/riv/wos
  • 000296112700007
http://linked.open...n/vavai/riv/zamer
issn
  • 1568-9883
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.hal.2011.04.013
http://localhost/t...ganizacniJednotka
  • 16270
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