About: Tularemia induces different biochemical responses in BALB/c mice and common voles.

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About: Tularemia induces different biochemical responses in BALB/c mice and common voles. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Background: Both BALB/c mice and common voles (Microtus arvalis) are considered highly susceptible to tularemia. However, the common vole is reported to harbour Francisella tularensis in European habitats as well as to survive longer with chronic shedding of the bacterium. The purpose of the present study was to compare the response of these two rodents to a wild Francisella tularensis subsp. holarctica strain infection. Methods: Rodents were evaluated for differences in the total antioxidant capacity derived from low-molecular-weight antioxidants, biochemistry including lipid metabolism, tissue bacterial burdens and histopathology following experimental intraperitoneal infection with 160 colony forming units (CFU) pro toto. Results: Bacterial burdens in common voles started to develop later post-exposure and amounted to lower levels than in BALB/c mice. Elevation of liver function enzymes was more pronounced in mice than common voles and there were marked differences in lipid metabolism in the cour Background: Both BALB/c mice and common voles (Microtus arvalis) are considered highly susceptible to tularemia. However, the common vole is reported to harbour Francisella tularensis in European habitats as well as to survive longer with chronic shedding of the bacterium. The purpose of the present study was to compare the response of these two rodents to a wild Francisella tularensis subsp. holarctica strain infection. Methods: Rodents were evaluated for differences in the total antioxidant capacity derived from low-molecular-weight antioxidants, biochemistry including lipid metabolism, tissue bacterial burdens and histopathology following experimental intraperitoneal infection with 160 colony forming units (CFU) pro toto. Results: Bacterial burdens in common voles started to develop later post-exposure and amounted to lower levels than in BALB/c mice. Elevation of liver function enzymes was more pronounced in mice than common voles and there were marked differences in lipid metabolism in the cour (en)
Title	Tularemia induces different biochemical responses in BALB/c mice and common voles. Tularemia induces different biochemical responses in BALB/c mice and common voles. (en)
skos:prefLabel	Tularemia induces different biochemical responses in BALB/c mice and common voles. Tularemia induces different biochemical responses in BALB/c mice and common voles. (en)
skos:notation	RIV/62157124:16270/09:00002244!RIV10-MSM-16270___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(OVUOFVZ200901), Z(MSM6215712402)
http://linked.open...iv/cisloPeriodika	9
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Novotný, Ladislav Vitula, František Treml, František Horáková, Jana Banďouchová, Hana Pikula, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Veterinární a farmaceutická univerzita Brno / Fakulta veterinární hygieny a ekologie
http://linked.open...dnocenehoVysledku	347064
http://linked.open...ai/riv/idVysledku	RIV/62157124:16270/09:00002244
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Francisella tularensis; Pathogenesis (en)
http://linked.open.../riv/klicoveSlovo	Pathogenesis Francisella tularensis
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[3E16B003622A]
http://linked.open...i/riv/nazevZdroje	BMC Infectious Diseases
http://linked.open...in/vavai/riv/obor	GJ
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Classification of biological agents – support of an international project „Establishment and management of a common database of B-agents – A European Laboratory Biodefence Network
http://linked.open...UplatneniVysledku	2009
http://linked.open...iv/tvurceVysledku	Banďouchová, Hana Novotný, Ladislav Pikula, Jiří Sedláčková, Jana Treml, František Vitula, František Pohanka, Martin Hubalek, Miroslav
http://linked.open...ain/vavai/riv/wos	000268568900002
http://linked.open...n/vavai/riv/zamer	Veterinary aspects of food safety and quality
issn	1471-2334
number of pages	9 (xsd:int)
http://localhost/t...ganizacniJednotka	16270

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